C
Charlotte E. Teunissen
Researcher at VU University Amsterdam
Publications - 622
Citations - 24213
Charlotte E. Teunissen is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Medicine & Dementia. The author has an hindex of 67, co-authored 475 publications receiving 16275 citations. Previous affiliations of Charlotte E. Teunissen include Philips & Vanderbilt University Medical Center.
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Journal ArticleDOI
Neurofilaments as biomarkers in neurological disorders
Michael Khalil,Charlotte E. Teunissen,Markus Otto,Fredrik Piehl,Maria Pia Sormani,Thomas Gattringer,Christian Barro,Ludwig Kappos,Manuel Comabella,Franz Fazekas,Axel Petzold,Kaj Blennow,Kaj Blennow,Henrik Zetterberg,Jens Kuhle +14 more
TL;DR: How technological advances have enabled the detection of neurofilament proteins in the blood is considered, and how these proteins consequently have the potential to be easily measured biomarkers of neuroaxonal injury in various neurological conditions are discussed.
Journal ArticleDOI
A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking
Charlotte E. Teunissen,Axel Petzold,Jeffrey Bennett,Frode S. Berven,Lou Brundin,Manuel Comabella,Diego Franciotta,Jette L. Frederiksen,John O. Fleming,Roberto Furlan,Rogier Q. Hintzen,S Hughes,M. H. Johnson,Eva Krasulova,Jens Kuhle,Maria Chiara Magnone,Cecilia Rajda,Konrad Rejdak,Hollie Schmidt,Vincent Van Pesch,Emmanuelle Waubant,Christian Wolf,Gavin Giovannoni,Bernhard Hemmer,Hayrettin Tumani,Florian Deisenhammer +25 more
TL;DR: A consensus report on recommendations for CSF collection and biobanking is presented, formed by the BioMS-eu network forCSF biomarker research in multiple sclerosis, and focuses on CSf collection procedures, preanalytical factors, and high-quality clinical and paraclinical information.
Journal ArticleDOI
Diagnostic value of plasma phosphorylated tau181 in Alzheimer's disease and frontotemporal lobar degeneration.
Elisabeth H. Thijssen,Elisabeth H. Thijssen,Renaud La Joie,Amy Wolf,Amelia Strom,Ping Wang,Leonardo Iaccarino,Viktoriya Bourakova,Yann Cobigo,Hilary W. Heuer,Salvatore Spina,Lawren VandeVrede,Xiyun Chai,Nicholas K. Proctor,David C. Airey,Sergey Shcherbinin,Cynthia Duggan Evans,John R. Sims,Henrik Zetterberg,Kaj Blennow,Kaj Blennow,Anna Karydas,Charlotte E. Teunissen,Joel H. Kramer,Lea T. Grinberg,William W. Seeley,Howie Rosen,Bradley F. Boeve,Bruce L. Miller,Gil D. Rabinovici,Jeffrey L. Dage,Julio C. Rojas,Adam L. Boxer +32 more
TL;DR: Plasma pTau181 concentrations are elevated specifically in patients diagnosed with Alzheimer’s disease compared to those diagnosed with frontotemporal lobar degeneration or elderly controls, supporting its further development as a blood-based biomarker for AD.
Journal ArticleDOI
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis
Claire Bridel,van Wieringen Wn,Henrik Zetterberg,Betty M. Tijms,Charlotte E. Teunissen,José C. Álvarez-Cermeño,Ulf Andreasson,Markus Axelsson,David Bäckström,Ales Bartos,Maria Bjerke,Kaj Blennow,Kaj Blennow,A. Boxer,Lena Brundin,Joachim Burman,Tove Christensen,Lenka Fialová,Lars Forsgren,Jette L. Frederiksen,Magnus Gisslén,Elizabeth Gray,Martin Gunnarsson,Sara Hall,Oskar Hansson,Megan K. Herbert,Joel Jakobsson,Jessen-Krut J,Shorena Janelidze,Gudmundur Johannsson,Gudmundur Johannsson,Michael Jonsson,Ludwig Kappos,Mohsen Khademi,Mohsen Khademi,Michael Khalil,Jens Kuhle,Mikael Landén,Leinonen,Giancarlo Logroscino,Lu Ch,Jan Lycke,Nadia K. Magdalinou,Andrea Malaspina,Niklas Mattsson,Lieke H.H. Meeter,Mehta,Signe Modvig,Tomas Olsson,Tomas Olsson,Ross W. Paterson,Pérez-Santiago J,Fredrik Piehl,Fredrik Piehl,Pijnenburg Yal,Pyykkö Ot,Ragnarsson O,Julio C. Rojas,Romme Christensen J,Sandberg L,Carole Scherling,Jonathan M. Schott,Finn Sellebjerg,Isabella Laura Simone,Tobias Skillbäck,Stilund M,Peter Sundström,Anders Svenningsson,Rosanna Tortelli,Carla Tortorella,Alessandro Trentini,Troiano M,Martin R Turner,van Swieten Jc,Mattias Vågberg,Marcel M. Verbeek,Luisa M. Villar,Pieter Jelle Visser,Pieter Jelle Visser,Anders Wallin,Weiss A,Carsten Wikkelsö,Edward J. Wild +82 more
TL;DR: The cNfL increased with age in HC and a majority of neurological conditions, although the association was strongest in HC, and has potential to assist the differentiation of FTD from AD and PD from atypical parkinsonian syndromes.
Journal ArticleDOI
Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status
Daphne Y.S. Vogel,E.J.F. Vereyken,Judith E. Glim,Priscilla D. A. M. Heijnen,Martina Moeton,Paul van der Valk,Sandra Amor,Sandra Amor,Charlotte E. Teunissen,Jack van Horssen,Christine D. Dijkstra +10 more
TL;DR: Although macrophages in active MS lesions predominantly display M1 characteristics, a major subset of macrophage have an intermediate activation status, as shown by the findings of this study.