W
Wendy E. Heywood
Researcher at University College London
Publications - 74
Citations - 2067
Wendy E. Heywood is an academic researcher from University College London. The author has contributed to research in topics: Medicine & Disease. The author has an hindex of 18, co-authored 56 publications receiving 1327 citations. Previous affiliations of Wendy E. Heywood include UCL Institute of Child Health & Great Ormond Street Hospital.
Papers
More filters
Journal ArticleDOI
Increased cerebrospinal fluid soluble TREM2 concentration in Alzheimer’s disease
Amanda Heslegrave,Wendy E. Heywood,Ross W. Paterson,Nadia K. Magdalinou,Johan Svensson,Per Johansson,Annika Öhrfelt,Kaj Blennow,John Hardy,Jonathan M. Schott,Kevin Mills,Henrik Zetterberg,Henrik Zetterberg +12 more
TL;DR: A mass spectrometry method using selected reaction monitoring for the presence of a TREM2 peptide is developed, which can be used to quantify levels of sTREM2 in CSF, and correlate with markers of neurodegeneration.
Journal ArticleDOI
Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure
Catherine J. Reynolds,Corinna Pade,Joseph Gibbons,Diana Munoz Sandoval,George Joy,Nasim Forooghi,Charlotte Manisty,James C. Moon,Rosemary J. Boyton,Hakam Abbass,Aderonke Abiodun,Mashael Alfarih,Zoe Alldis,Daniel M. Altmann,Oliver E. Amin,Mervyn Andiapen,Jessica Artico,João B Augusto,Georgina L Baca,Sasha N. L. Bailey,Anish N Bhuva,Alex Boulter,Ruth Bowles,Olivia V Bracken,Ben O’Brien,Tim Brooks,Natalie Bullock,David Butler,Gabriella Captur,Olivia Carr,Nicola Champion,Carmen Chan,Aneesh Chandran,Tom Coleman,Jorge Couto de Sousa,Xose Couto-Parada,Eleanor Cross,Teresa Cutino-Moguel,Silvia D'Arcangelo,Rhodri H Davies,Brooke Douglas,Cecilia Di Genova,Keenan Dieobi-Anene,Mariana O. Diniz,Ana Gabriela Aguilar Ellis,Karen Feehan,M. Finlay,Marianna Fontana,Sasha Francis,David Gillespie,Derek W. Gilroy,Matt Hamblin,Gabriella Harker,Georgia C. Hemingway,Jacqueline Hewson,Wendy E. Heywood,Lauren M. Hickling,Bethany Hicks,Aroon D. Hingorani,Lee Howes,Ivie Itua,Victor Jardim,Wing-Yiu Jason Lee,Melanie Jensen,Jessica Jones,Meleri Jones,V. S. Kapil,Caoimhe Kelly,H. Kurdi,Jonathan Lambourne,Kai-Min Lin,Siyi Liu,Aaron Lloyd,Sarah Louth,Mala K. Maini,Vineela Mandadapu,Áine McKnight,Katia Menacho,C. Mfuko,Kevin Mills,Sebastian Millward,Oliver Mitchelmore,Christopher William Moon,Sam M. Murray,Mahdad Noursadeghi,Ashley Otter,Susana Palma,Ruth Parker,Kush Patel,Mihaela Pawarova,Steffen E. Petersen,Brian Piniera,Franziska P Pieper,Lisa Rannigan,Alicja Rapala,Amy Richards,Matthew Robathan,Joshua Rosenheim,Cathy Rowe,M Royds,Jane Sackville West,Genine Sambile,Nathalie Schmidt,Hannah Selman,Amanda Semper,Andreas Seraphim,Mihaela Simion,Angelique Smit,Michelle Sugimoto,Leo Swadling,Stephen Taylor,Nigel J. Temperton,Stephen Thomas,George Douglas Thornton,Thomas A. Treibel,Arthur Tucker,A. Varghese,Jessry Veerapen,Mohit Vijayakumar,Time Warner,Sophie Welch,Hannah White,Theresa Wodehouse,Lucinda Wynne,Dan Zahedi,Benjamin M. Chain +125 more
TL;DR: B and T cell immunity against previous variants of concern was enhanced in triple vaccinated individuals, but magnitude of T and B cell responses against B.1.1 .1.529 spike protein was reduced.
Journal ArticleDOI
Ambroxol for the Treatment of Patients With Parkinson Disease With and Without Glucocerebrosidase Gene Mutations: A Nonrandomized, Noncontrolled Trial.
Stephen Mullin,Stephen Mullin,Laura Smith,Katherine Lee,Gayle D’Souza,Philip Woodgate,Josh Elflein,Jenny Hällqvist,Marco Toffoli,Adam Streeter,Joanne Hosking,Wendy E. Heywood,Rajeshree Khengar,Philip Campbell,Jason Hehir,Sarah Cable,Kevin Mills,Henrik Zetterberg,Patricia Limousin,Vincenzo Libri,Thomas Foltynie,Anthony H.V. Schapira +21 more
TL;DR: Ambroxol therapy has potential for study as a neuroprotective compound for the treatment of patients with Parkinson disease both with and without glucocerebrosidase gene mutations.
Journal ArticleDOI
Application of label-free absolute quantitative proteomics in human gingival crevicular fluid by LC/MS E (gingival exudatome)
TL;DR: The aim of this study was to perform analysis of the GCF exudatome from healthy and periodontally diseased sites by LC/MS(E), a label-free mass spectrometry method that enables simultaneous protein identification and absolute quantification in biological fluids, and to facilitate characterization of GCF proteome in periodontal health and disease.
Journal ArticleDOI
Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study
Viola Volpato,James Smith,Cynthia Sandor,Janina S. Ried,Anna Baud,Adam E. Handel,Sarah E. Newey,Frank Wessely,Moustafa Attar,Emma S. Whiteley,Satyan Chintawar,An Verheyen,Thomas Barta,Majlinda Lako,Lyle Armstrong,Caroline Muschet,Aanna Artati,Carlo Cusulin,Klaus Christensen,Christoph Patsch,Eshita Sharma,Jérôme Nicod,Philip W. Brownjohn,Victoria Stubbs,Wendy E. Heywood,Paul Gissen,Roberta De Filippis,Katharina Janssen,Peter Reinhardt,Jerzy Adamski,Ines Royaux,Pieter J. Peeters,Georg C. Terstappen,Martin Graf,Frederick J. Livesey,Colin J. Akerman,Kevin Mills,Rory Bowden,George Nicholson,Caleb Webber,M. Zameel Cader,Viktor Lakics +41 more
TL;DR: This study shows that multi-center collaborations can expose systematic biases and identify critical factors to be standardized when publishing novel protocols, contributing to increased cross-site reproducibility.