N
Niels Voigt
Researcher at University of Göttingen
Publications - 131
Citations - 7369
Niels Voigt is an academic researcher from University of Göttingen. The author has contributed to research in topics: Atrial fibrillation & Ryanodine receptor. The author has an hindex of 37, co-authored 117 publications receiving 6219 citations. Previous affiliations of Niels Voigt include University of Duisburg-Essen & Dresden University of Technology.
Papers
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Journal ArticleDOI
Nucleoside Diphosphate Kinase-C Suppresses cAMP Formation in Human Heart Failure.
Issam Abu-Taha,Jordi Heijman,Hans-Jörg Hippe,Nadine M. Wolf,Ali El-Armouche,Viacheslav O. Nikolaev,Marina Schäfer,Christina M. Würtz,Stefan Neef,Niels Voigt,István Baczkó,András Varró,Marion Müller,Benjamin Meder,Hugo A. Katus,Katharina Spiger,Christiane Vettel,Lorenz H. Lehmann,Johannes Backs,Edward Y. Skolnik,Susanne Lutz,Dobromir Dobrev,Thomas Wieland +22 more
TL;DR: NDPK-C is a novel critical regulator of &bgr;-adrenoceptor/cAMP signaling and cardiac contractility and may contribute to lower cAMP levels and the related contractile dysfunction in HF by switching from G&agr;s to G&AGr;i2 activation.
Journal ArticleDOI
CaMKII activity contributes to homeometric autoregulation of the heart: A novel mechanism for the Anrep effect.
Jan-Christian Reil,Gert-Hinrich Reil,Árpád Kovács,Vasco Sequeira,Mark T. Waddingham,Mária Lódi,Melissa Herwig,Shahrooz Ghaderi,Michael M. Kreusser,Zoltán Papp,Niels Voigt,Niels Voigt,Dobromir Dobrev,Svenja Meyhöfer,Harald F. Langer,Lars S. Maier,Dominik Linz,Andreas Mügge,Mathias Hohl,Paul Steendijk,Nazha Hamdani +20 more
TL;DR: The Anrep effect represents the alteration of left ventricular contractility to acutely enhanced afterload in a few seconds, thereby preserving stroke volume (SV) at constant preload, and might present a new facet of subcellular signalling with respect to cardiovascular regulation.
Book ChapterDOI
Voltage-Clamp-Based Methods for the Detection of Constitutively Active Acetylcholine-Gated IK,ACh Channels in the Diseased Heart
TL;DR: This chapter provides an overview of the voltage-clamp techniques that can be used to study constitutive I(K,ACh) activity in atrial myocytes and summarizes briefly the current knowledge about the potential underlying mechanism(s) of constitutive IIACh activity in diseased heart.
Journal ArticleDOI
The combined effects of ranolazine and dronedarone on human atrial and ventricular electrophysiology.
Nico Hartmann,Fleur E. Mason,Inga Braun,Steffen Pabel,Niels Voigt,Hanna Schotola,Thomas H. Fischer,Dobromir Dobrev,Bernhard C. Danner,André Renner,Jan Gummert,Luiz Belardinelli,Norbert Frey,Lars S. Maier,Gerd Hasenfuss,Samuel Sossalla,Samuel Sossalla +16 more
TL;DR: Electrophysiological measurements during exposure to ranolazine alone or in combination with low-dose dronedarone showed APD prolongation, cellular hyperpolarization and reduced SR Ca(2+) leak in human atrial myocytes.