P
Patrick Duriez
Researcher at university of lille
Publications - 49
Citations - 1693
Patrick Duriez is an academic researcher from university of lille. The author has contributed to research in topics: Apolipoprotein B & Cholesterol. The author has an hindex of 22, co-authored 49 publications receiving 1591 citations. Previous affiliations of Patrick Duriez include French Institute of Health and Medical Research & Lille University of Science and Technology.
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Journal ArticleDOI
PPAR: a new pharmacological target for neuroprotection in stroke and neurodegenerative diseases.
Régis Bordet,Thavarak Ouk,Olivier Pétrault,Patrick Gelé,Sophie Gautier,M. Laprais,Dominique Deplanque,Patrick Duriez,Bart Staels,Jean-Charles Fruchart,Michèle Bastide +10 more
TL;DR: Beyond neuroprotection in cerebral ischaemia, PPARs are also pertinent pharmacological targets to induce neuro protection in chronic neurodegenerative diseases.
Journal ArticleDOI
Apolipoprotein A-II, HDL metabolism and atherosclerosis
TL;DR: It can be suggested that apo A-II is not a strong determinant of lipid metabolism, but is rather a modulator of reverse cholesterol transport, which might improve reverse cholesterol Transport and might reduce atherosclerosis development while some other effects might be deleterious.
Journal ArticleDOI
Modified low density lipoproteins activate human macrophages to secrete immunoreactive endothelin
Françoise Martin-Nizard,Françoise Martin-Nizard,Hayat Sqalli Houssaini,Hayat Sqalli Houssaini,S. Lestavel-Delattre,S. Lestavel-Delattre,Patrick Duriez,Patrick Duriez,Jean-Charles Fruchart,Jean-Charles Fruchart +9 more
TL;DR: In conclusion, mod stimulated ET secretion by human macrophages is concluded.
Journal ArticleDOI
The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential
Jean-Charles Fruchart,Raul D. Santos,Carlos A. Aguilar-Salinas,Masanori Aikawa,Khalid Al Rasadi,Pierre Amarenco,Philip J. Barter,Richard Ceska,Alberto Corsini,Jean-Pierre Després,Patrick Duriez,Robert H. Eckel,Marat V. Ezhov,Michel Farnier,Henry N. Ginsberg,Michel P. Hermans,Shun Ishibashi,Fredrik Karpe,Tatsuhiko Kodama,Wolfgang Koenig,Wolfgang Koenig,Michel Krempf,Michel Krempf,Soo Lim,Alberto J. Lorenzatti,Ruth McPherson,Jesús Millán Núñez-Cortés,Børge G. Nordestgaard,Børge G. Nordestgaard,Hisao Ogawa,Chris J. Packard,Jorge Plutzky,Carlos I. Ponte-Negretti,Aruna D. Pradhan,Aruna D. Pradhan,Kausik K. Ray,Željko Reiner,Paul M. Ridker,Massimiliano Ruscica,Shaukat Sadikot,Hitoshi Shimano,Piyamitr Sritara,Jane K Stock,Ta-Chen Su,Andrey V. Susekov,André Tartar,Marja-Riitta Taskinen,Alexander Tenenbaum,Alexander Tenenbaum,Lale Tokgozoglu,Brian Tomlinson,Anne Tybjærg-Hansen,Anne Tybjærg-Hansen,Paul Valensi,Michal Vrablík,Walter Wahli,Walter Wahli,Walter Wahli,Gerald F. Watts,Shizuya Yamashita,Koutaro Yokote,Alberto Zambon,Peter Libby +62 more
TL;DR: In this paper, the authors developed a selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) for the treatment of atherogenic dyslipidemia.
Journal ArticleDOI
Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits.
Michael I. Mackness,Agnes Bouiller,Nathalie Hennuyer,Bharti Mackness,Maxine Hall,Anne Tailleux,Patrick Duriez,Bernard Delfly,Paul N. Durrington,Jean-Charles Fruchart,Nicolas Duverger,Jean-Michel Caillaud,Graciela Castro +12 more
TL;DR: The relationship between PON1 and atherosclerosis development in transgenic rabbits overexpressing human apolipoprotein (apo) A-I and nontransgenic littermates fed a pro-atherogenic diet is examined.