P
Paul M. Tulkens
Researcher at Université catholique de Louvain
Publications - 381
Citations - 19031
Paul M. Tulkens is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Aminoglycoside & Nephrotoxicity. The author has an hindex of 69, co-authored 377 publications receiving 17710 citations. Previous affiliations of Paul M. Tulkens include University College London & Catholic University of Leuven.
Papers
More filters
Journal ArticleDOI
Commentary. Lysosomotropic agents.
Journal ArticleDOI
Aminoglycosides: Activity and Resistance
TL;DR: Aminoglycosides are highly potent, broad-spectrum antibiotics with many desirable properties for the treatment of life-threatening infections and have a history marked by the successive introduction of a series of milestone compounds.
Journal ArticleDOI
Tackling antibiotic resistance
Karen Bush,Patrice Courvalin,Gautam Dantas,Julian Davies,Barry I. Eisenstein,Pentti Huovinen,George A. Jacoby,Roy Kishony,Barry N. Kreiswirth,Elizabeth Kutter,Stephen A. Lerner,Stuart B. Levy,Kim Lewis,Olga Lomovskaya,Jeffrey H Miller,Shahriar Mobashery,Laura J. V. Piddock,Steven J. Projan,Christopher M. Thomas,Alexander Tomasz,Paul M. Tulkens,Timothy R. Walsh,James D. Watson,Jan A. Witkowski,Wolfgang Witte,Gerry Wright,Pamela J. Yeh,Helen I. Zgurskaya +27 more
TL;DR: To explore how the problem of antibiotic resistance might best be addressed, a group of 30 scientists from academia and industry gathered at the Banbury Conference Centre in Cold Spring Harbor, New York, USA, from 16 to 18 May 2011.
Journal ArticleDOI
Antibiotic efflux pumps.
TL;DR: The existence of antibiotic efflux pumps, and their impact on therapy, must be taken fully into account for the selection of novel antimicrobials, and the design of specific, potent inhibitors appears to be an important goal for the improved control of infectious diseases in the near future.
Journal ArticleDOI
Quinolones in 2005: an update
TL;DR: Overall, it is concluded that these important agents should be used in an educated fashion, based on a careful balance between their ease of use and efficacy vs. the risk of emerging resistance and toxicity.