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Paul M. Tulkens

Researcher at Université catholique de Louvain

Publications -  381
Citations -  19031

Paul M. Tulkens is an academic researcher from Université catholique de Louvain. The author has contributed to research in topics: Aminoglycoside & Nephrotoxicity. The author has an hindex of 69, co-authored 377 publications receiving 17710 citations. Previous affiliations of Paul M. Tulkens include University College London & Catholic University of Leuven.

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Aminoglycosides: Activity and Resistance

TL;DR: Aminoglycosides are highly potent, broad-spectrum antibiotics with many desirable properties for the treatment of life-threatening infections and have a history marked by the successive introduction of a series of milestone compounds.
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Antibiotic efflux pumps.

TL;DR: The existence of antibiotic efflux pumps, and their impact on therapy, must be taken fully into account for the selection of novel antimicrobials, and the design of specific, potent inhibitors appears to be an important goal for the improved control of infectious diseases in the near future.
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Quinolones in 2005: an update

TL;DR: Overall, it is concluded that these important agents should be used in an educated fashion, based on a careful balance between their ease of use and efficacy vs. the risk of emerging resistance and toxicity.