Pamela J. Yeh

TL;DR: To explore how the problem of antibiotic resistance might best be addressed, a group of 30 scientists from academia and industry gathered at the Banbury Conference Centre in Cold Spring Harbor, New York, USA, from 16 to 18 May 2011.

TL;DR: The results provide the first quantitative support of Baldwin’s proposition that plasticity can be crucial for population persistence during the early stages of colonization.

TL;DR: A sensitive bioluminescence technique is used to provide quantitative measurements of pairwise interactions among 21 antibiotics that affect growth rate in Escherichia coli and finds that the drug interaction network possesses a special property: it can be separated into classes of drugs such that any two classes interact either purely synergistically or purely antagonistically.

TL;DR: Drug antagonism is emerging as a powerful tool to study biological function and relatedness between cellular components as well as to uncover mechanisms of drug action.

TL;DR: It is suggested that selection strength is an important parameter contributing to the complexity of antibiotic resistance problem and use of high doses of antibiotics to clear infections has the potential to promote increase of cross-resistance in clinics.