P
Peter Arner
Researcher at Karolinska Institutet
Publications - 565
Citations - 56932
Peter Arner is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Adipose tissue & Lipolysis. The author has an hindex of 114, co-authored 553 publications receiving 52710 citations. Previous affiliations of Peter Arner include Karolinska University Hospital & Bristol-Myers Squibb.
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Journal ArticleDOI
Expression of nitric oxide synthases in subcutaneous adipose tissue of nonobese and obese humans.
Montserrat Elizalde,Mikael Rydén,Vanessa van Harmelen,Peter Eneroth,Hans Gyllenhammar,Cecilia Holm,Stig Ramel,Anders Ölund,Peter Arner,Kurt Andersson +9 more
TL;DR: It is speculated that increased NO production, preferably by eNOS, and decreased HSL levels may cause decreased subcutaneous adipose tissue lipolysis in obesity.
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Increased fat cell size: a major phenotype of subcutaneous white adipose tissue in non-obese individuals with type 2 diabetes
Juan R. Acosta,Iyadh Douagi,Daniel P. Andersson,Jesper Bäckdahl,Mikael Rydén,Peter Arner,Jurga Laurencikiene +6 more
TL;DR: A major phenotype of white adipose tissue in non-obese individuals with type 2 diabetes is adipocyte hypertrophy, which may be mediated by an impaired adipogenic capacity in progenitor cells, which could have an impact on adiposes tissue inflammation, release of fatty acids, ectopic fat deposition and insulin sensitivity.
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NF-kappaB is important for TNF-alpha-induced lipolysis in human adipocytes.
Jurga Laurencikiene,Vanessa van Harmelen,Elisabet Arvidsson Nordström,Andrea Dicker,Lennart Blomqvist,Erik Näslund,Dominique Langin,Peter Arner,Mikael Rydén +8 more
TL;DR: It is concluded that in the presence of NF-kappaB inhibition, TNF-alpha-mediated lipolysis is reduced, which suggests that NF- kappaB is essential for retained human fat celllipolysis.
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Evidence for a functional β3‐adrenoceptor in man
TL;DR: It is suggested that human white fat cells express an atypical β‐adrenoceptor in addition to β1‐ and β2‐ adrenoceptors and is poorly sensitive to blockade by selective β1- andβ2‐antagonists.