P
Peter Arner
Researcher at Karolinska Institutet
Publications - 565
Citations - 56932
Peter Arner is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Adipose tissue & Lipolysis. The author has an hindex of 114, co-authored 553 publications receiving 52710 citations. Previous affiliations of Peter Arner include Karolinska University Hospital & Bristol-Myers Squibb.
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Journal ArticleDOI
Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects.
TL;DR: It is concluded that significant amounts of glycerol are released from skeletal muscle, which suggests that muscle lipolysis provides an important endogenous energy source in humans.
Journal ArticleDOI
Effects of weight reduction on the regulation of lipolysis in adipocytes of women with upper-body obesity
Signy Reynisdottir,Dominique Langin,Kjell Carlström,Cecilia Holm,Stephan Rössner,Peter Arner +5 more
TL;DR: Weight reduction leads to increased efficiency of adipocyte lipolysis with decreased restinglipolysis rate but increased sensitivity to stimulation by catecholamines, which may be attributed to a decreased activity of hormone-sensitive lipase and an increased sensitivity of beta 2-adrenoceptors.
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Long-Term Prospective and Controlled Studies Demonstrate Adipose Tissue Hypercellularity and Relative Leptin Deficiency in the Postobese State
P. Löfgren,Ingalena Andersson,Birgitta Adolfsson,Britt-Marie Leijonhufvud,Katarina Hertel,Johan Hoffstedt,Peter Arner +6 more
TL;DR: Adipose tissue hyperplasia (too many small fat cells) and low leptin production resulting in relative hypoleptinemia in the fasting (basal) state are common features of the postobese state in women.
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Secretion of tumor necrosis factor-alpha shows a strong relationship to insulin-stimulated glucose transport in human adipose tissue.
P. Löfgren,Vanessa Van Harmelen,Signy Reynisdottir,Erik Näslund,M. Rydén,Stephan Rössner,Peter Arner +6 more
TL;DR: In conclusion, adipose TNF-alpha may be an important specific and local factor in adipose tissue that influences the ability of insulin to stimulate glucose transport in human fat cells, at least in obese women.
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Action of glucagon and glucagon-like peptide-1-(7-36) amide on lipolysis in human subcutaneous adipose tissue and skeletal muscle in vivo
TL;DR: Isoprenaline, but not glucagon or GLP-1, stimulated lipolysis in vitro in isolated human sc adipose tissue and skeletal muscle, and it is concluded that neither glucagon nor GLp-1 affect the lipolytic rate of human sc obesity tissue or skeletal muscle.