P
Peter Arner
Researcher at Karolinska Institutet
Publications - 565
Citations - 56932
Peter Arner is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Adipose tissue & Lipolysis. The author has an hindex of 114, co-authored 553 publications receiving 52710 citations. Previous affiliations of Peter Arner include Karolinska University Hospital & Bristol-Myers Squibb.
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Journal ArticleDOI
Association of ADRB1 and UCP3 Gene Polymorphisms with Insulin Sensitivity but Not Obesity
Salim Mottagui-Tabar,Johan Hoffstedt,Anthony J. Brookes,Hong Jiao,Peter Arner,Ingrid Dahlman +5 more
TL;DR: Polymorphisms in ADRB1 and UCP3 may contribute to insulin resistance rather than obesity among Swedish women.
Journal ArticleDOI
Transcriptional Dynamics During Human Adipogenesis and its Link to Adipose Morphology and Distribution
Anna Ehrlund,Niklas Mejhert,Christel Björk,Robin Andersson,Agné Kulyté,Gaby Åström,Masayoshi Itoh,Hideya Kawaji,Timo Lassmann,Carsten O. Daub,Piero Carninci,Alistair R. R. Forrest,Yoshihide Hayashizaki,Albin Sandelin,Erik Ingelsson,Erik Ingelsson,Mikael Rydén,Jurga Laurencikiene,Peter Arner,Erik Arner +19 more
TL;DR: The transcriptional events that occur during in vitro differentiation of human adipocytes were investigated and the findings linked to WAT phenotypes suggest a complex but highly coordinated regulation of adipogenesis.
Journal ArticleDOI
Primary differences in lipolysis between human omental and subcutaneous adipose tissue observed using in vitro differentiated adipocytes.
Andrea Dicker,Gaby Åström,Kerstin Wåhlén,J Hoffstedt,Erik Näslund,Mikael Wirén,M. Rydén,Peter Arner,Vanessa van Harmelen +8 more
TL;DR: Using beta1-, beta2-, and beta3-adenoceptor agonists, lipolysis was found to be significantly higher in omental as compared to subcutaneous differentiated preadipocytes and ANP-inducedlipolysis is not subject to primary regional variation.
Journal ArticleDOI
MTCH2 in human white adipose tissue and obesity.
Agné Kulyté,Mikael Rydén,Niklas Mejhert,Elisabeth Dungner,Eva Sjölin,Peter Arner,Ingrid Dahlman +6 more
TL;DR: MTCH2 is highly expressed in human WAT and adipocytes with increased levels in obese women, suggesting that MTCH2 may play a role in cellular processes underlying obesity.
Adipocyte Turnover: Relevance to Human Adipose Tissue
Morphology Arner,Pål O. Westermark,Kirsty L. Spalding,Tom Britton,Samuel Bernard,Peter Arner +5 more
TL;DR: Adipose tissue morphology correlates with insulin measures and is linked to the total adipocyte number independently of sex and body fat level, and low generation rates of adipocytes associate with adipose tissue hypertrophy, whereas high generation rates associate withadipose hyperplasia.