P
Peter Arner
Researcher at Karolinska Institutet
Publications - 565
Citations - 56932
Peter Arner is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Adipose tissue & Lipolysis. The author has an hindex of 114, co-authored 553 publications receiving 52710 citations. Previous affiliations of Peter Arner include Karolinska University Hospital & Bristol-Myers Squibb.
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Journal ArticleDOI
Changes in the metabolism of fatty acids in adipose tissue in obese patients with primary hypertriacylglycerolemia.
TL;DR: It is concluded that, in adipose tissue of obese patients with primary hypertriacylglycerolemia, the esterification of free fatty acids to triacyl glycerol is decreased and, as a consequence,free fatty acids are mobilized at an increased rate.
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The Rho GTPase RND3 regulates adipocyte lipolysis.
Simon N. Dankel,Simon N. Dankel,Therese H. Røst,Agné Kulyté,Zinayida Fandalyuk,Thomas Skurk,Hans Hauner,Jørn V. Sagen,Mikael Rydén,Peter Arner,Gunnar Mellgren,Gunnar Mellgren +11 more
TL;DR: A novel differential expression of adipose R ND3 in obesity and insulin resistance is uncovered, which may at least partly depend on a causal effect of RND3 on adipocyte lipolysis.
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Free fatty acid determination by peroxidase catalysed luminol chemiluminescence
TL;DR: A sensitive, specific, and partly automatic method for the analysis of free fatty acids is described and AffiGel 501 was used to covalently bind the free thiol group in CoASH eliminating interference of this substance in the peroxidase-luminol reaction.
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LRIG proteins regulate lipid metabolism via BMP signaling and affect the risk of type 2 diabetes.
Carl Herdenberg,Pascal M. Mutie,Ola Billing,Ahmad Sharmi Abdullah,Rona J. Strawbridge,Rona J. Strawbridge,Ingrid Dahlman,Simon Tuck,Camilla Holmlund,Peter Arner,Roger Henriksson,Paul W. Franks,Håkan Hedman +12 more
TL;DR: This article showed that Lrig-null mouse embryonic fibroblasts (MEFs) are deficient in adipogenesis and bone morphogenetic protein (BMP) signaling and showed that LRIG proteins function as evolutionarily conserved regulators of lipid metabolism and BMP signaling and have implications for human disease.
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Interactions between adenylate cyclase inhibitors and beta-adrenoceptors in isolated human fat cells.
Fredrik Lönnqvist,Peter Arner +1 more
TL;DR: It is concluded that the affinity of human fat cell beta-adrenoceptors is reduced by adenylate cyclase inhibitors, and this seems to be mediated by the Gi-protein and represents a new potential mechanism by which lipolysis is regulated by inhibitors of adenYLate Cyclase in man.