P
Peter Arner
Researcher at Karolinska Institutet
Publications - 565
Citations - 56932
Peter Arner is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Adipose tissue & Lipolysis. The author has an hindex of 114, co-authored 553 publications receiving 52710 citations. Previous affiliations of Peter Arner include Karolinska University Hospital & Bristol-Myers Squibb.
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Journal ArticleDOI
Additive Effects of MicroRNAs and Transcription Factors on CCL2 Production in Human White Adipose Tissue
Agné Kulyté,Yasmina Belarbi,Silvia Lorente-Cebrián,Clara Bambace,Erik Arner,Carsten O. Daub,Per Hedén,Mikael Rydén,Niklas Mejhert,Peter Arner +9 more
TL;DR: TF and miRNA-mediated regulation of CCL2 production is additive and partly relayed by cell-specific networks in human adipose tissue that may be important for the development of insulin resistance/type 2 diabetes.
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Marked increase in insulin sensitivity of human fat cells 1 hour after glucose ingestion
TL;DR: It is concluded that glucose ingestion is accompanied by a marked increase in insulin sensitivity of human fat cells and this may be an important modulating factor in the overall scheme of insulin action.
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Major differences in noradrenaline action on lipolysis and blood flow rates in skeletal muscle and adipose tissue in vivo.
TL;DR: Lipolysis and blood flow rates are regulated differently in adipose tissue and skeletal muscle, and physiological concentrations of noradrenaline decrease blood flow but have no stimulatory effect on lipolysis rates.
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The Adipose Transcriptional Response to Insulin Is Determined by Obesity, Not Insulin Sensitivity.
Mikael Rydén,Olga Hrydziuszko,Enrichetta Mileti,Amitha Raman,Jette Bornholdt,Mette Boyd,Eva Toft,Eva Toft,Veronica Qvist,Veronica Qvist,Erik Näslund,Anders Thorell,Daniel P. Andersson,Ingrid Dahlman,Ingrid Dahlman,Hui Gao,Albin Sandelin,Carsten O. Daub,Peter Arner +18 more
TL;DR: It is demonstrated that differences in the acute transcriptional response to insulin are primarily driven by obesity per se, challenging the notion of healthy obese adipose tissue, at least in severe obesity.
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Relationship between the tissue level of cyclic AMP and the fat cell size of human adipose tissue.
Peter Arner,Jan Östman +1 more
TL;DR: It is concluded that basal and catecholamine-induced production of cyclic AMP is related to the fat cell size and that a quantitative relationship exists between rate of lipolysis and maximal tissue levels of cyclIC AMP in human adipose tissue.