P
Philip L. Lorenzi
Researcher at University of Texas MD Anderson Cancer Center
Publications - 128
Citations - 22127
Philip L. Lorenzi is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 37, co-authored 96 publications receiving 17665 citations. Previous affiliations of Philip L. Lorenzi include University of Michigan & Loyola University Chicago.
Papers
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Journal ArticleDOI
PKM1 Exerts Critical Roles in Cardiac Remodeling Under Pressure Overload in the Heart
Qinfeng Li,Qinfeng Li,Chao Li,Abdallah Elnwasany,Gaurav Sharma,Yu An,Guangyu Zhang,Waleed M. Elhelaly,Jun Lin,Yingchao Gong,Guihao Chen,Meihui Wang,Shangang Zhao,Chongshan Dai,Charles D. Smart,Juan Liu,Xiang Luo,Yingfeng Deng,Lin Tan,Shuang Jie Lv,Shawn M. Davidson,Jason W. Locasale,Philip L. Lorenzi,Craig R. Malloy,Thomas G. Gillette,Matthew G. Vander Heiden,Matthew G. Vander Heiden,Philipp E. Scherer,Luke I. Szweda,Guosheng Fu,Zhao V. Wang +30 more
TL;DR: The elevation of glucose utilization has been recognized as a hallmark of metabolic remodeling during cardiac hypertrophic growth under hemodynamic stress as mentioned in this paper, and it has been shown that metabolic remodeling precedes most alterations during cardiac hypertension.
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Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
Eiko Hayase,Tomoyoshi Hayase,Mohamed A. Jamal,Takahiko Miyama,Chia-Chi Chang,Miriam R. Ortega,Saira Ahmed,Jennifer Karmouch,Christopher A. Sanchez,Alexandria N. Brown,Rawan K. El-Himri,Ivonne Flores,Lauren K. McDaniel,Dung T. Pham,Taylor Halsey,Annette C. Frenk,Valerie Chapa,Brooke Heckel,Yimei Jin,Wen Bin Tsai,Rishika Prasad,Lin Tan,Lucas Veillon,Nadim J. Ajami,Jennifer A. Wargo,Jessica Galloway-Peña,Samuel A. Shelburne,Roy F. Chemaly,Lauren Davey,Robert W. P. Glowacki,Chen Liu,Gabriela Rondon,Amin M. Alousi,Jeffrey J. Molldrem,Richard E. Champlin,Elizabeth J. Shpall,Raphael H. Valdivia,Eric C. Martens,Philip L. Lorenzi,Robert R. Jenq +39 more
TL;DR: The use of meropenem aggravates colonic GVHD, at least in part via expansion of Bacteroides thetaiotaomicron (BT) as mentioned in this paper .
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Lipidomic Profiles of Plasma Exosomes Identify Candidate Biomarkers for Early Detection of Hepatocellular Carcinoma in Patients with Cirrhosis.
Jessica I. Sanchez,Jingjing Jiao,Suet Ying Kwan,Lucas Veillon,Marc O. Warmoes,Lin Tan,Mobolaji Odewole,Nicole E. Rich,Peng Wei,Philip L. Lorenzi,Amit G. Singal,Laura Beretta +11 more
TL;DR: In this paper, exosomes and their lipid content in particular represent potentially valuable noninvasive diagnostic biomarkers for hepatocellular carcinoma surveillance in cirrhotic patients.
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N-methylpurine DNA glycosylase and 8-oxoguanine DNA glycosylase metabolize the antiviral nucleoside 2-bromo-5,6-dichloro-1-(β-D-ribofuranosyl)benzimidazole
Philip L. Lorenzi,Christopher P. Landowski,Christopher P. Landowski,Andrea Brancale,Xueqin Song,Leroy B. Townsend,John C. Drach,Gordon L. Amidon +7 more
TL;DR: The identification of two enzymes, 8-oxoguanine DNA glycosylase (OGG1) and N-methylpurine DNA Glycosylases (MPG), that catalyze N-glycosidic bond cleavage of BDCRB and its 2-chloro homolog, 2,5,6-trichloro-1-(β-d-ribofuranosyl)benzimidazole, but not maribavir are
Journal ArticleDOI
Suppression of Membranous LRP5 Recycling, Wnt/β-Catenin Signaling, and Colon Carcinogenesis by 15-LOX-1 Peroxidation of Linoleic Acid in PI3P.
Fuyao Liu,Xiangsheng Zuo,Yi Liu,Yasunori Deguchi,Micheline J. Moussalli,Weidong Chen,Peiying Yang,Bo Wei,Lin Tan,Philip L. Lorenzi,Shen Gao,Jonathan C. Jaoude,Amir Mehdizadeh,Lovie Ann Valentin,Daoyan Wei,Imad Shureiqi +15 more
TL;DR: It is reported that high dietary LA promotes CRC in mice treated with azoxymethane or with an intestinally targeted Apc mutation by upregulating Wnt receptor LRP5 protein expression and β-catenin activation.