Pius Brzoska

TL;DR: It is shown that lincRNAs in the HOX loci become systematically dysregulated during breast cancer progression, indicating that l incRNAs have active roles in modulating the cancer epigenome and may be important targets for cancer diagnosis and therapy.

TL;DR: It is suggested that by stepwise gain and loss of chromosomal and plasmid-encoded virulence factors, a highly pathogenic hybrid of EAEC and EHEC emerged as the current outbreak clone.

TL;DR: It is found that allelic imbalance in the tumor is associated with Copy number mutations and that copy number mutations are, in turn, strongly associated with changes in transcript abundance, which support a model in which allele-specific deletions and duplications drive allele- specific changes in gene expression in the developing tumor.

TL;DR: C. sakazakii is unique in the Cronobacter genus in encoding genes enabling the utilization of exogenous sialic acid which may have clinical significance, and also suggested various degrees of divergence.

TL;DR: The Quantifiler HP and Trio Kits' improved performance provides better predictive ability for results with downstream, newest-generation STR assays, and their shortened time-to-result allows more efficient integration into the forensic casework analysis workflow.