Qizhai Li

TL;DR: Strong genome-wide significant associations with 25(OH)D are confirmed through meta-analysis with the GWAS data for GC, NADSYN1/DHCR7, CYP2R1 and CYP 2R1, but not C10orf88, the key C-25 hydroxylase that converts vitamin D3 to an active vitamin D receptor ligand.

TL;DR: A lung cancer GWAS identified a distinct hereditary contribution to adenocarcinoma, and previously reported association signals on 15q25 and 6p21 were refined, but no additional loci reached genome-wide significance.

TL;DR: It is found that NKAPL and ZKSCAN4 were expressed in postnatal day 0 (P0) mouse brain and may lead to new insights into the pathogenesis of schizophrenia.

TL;DR: It is demonstrated through simulation studies that a gene‐based analysis that treats the underlying genes, as opposed to the underlying SNPs, as the basic units for hypothesis testing, is a very robust and powerful approach to pathway‐based association testing.

TL;DR: Empirical data from two GWAS in European Americans of the Cancer Genetic Markers of Susceptibility project were used to evaluate the impact of PS in studies with different control selection strategies, finding that a study using suboptimal controls can have acceptable type I error when an effective strategy for the correction of PS is employed.