M
Mark P. Purdue
Researcher at National Institutes of Health
Publications - 402
Citations - 24024
Mark P. Purdue is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Population & Cancer. The author has an hindex of 73, co-authored 372 publications receiving 19823 citations. Previous affiliations of Mark P. Purdue include Ontario Institute for Cancer Research & United States Department of Health and Human Services.
Papers
More filters
Journal ArticleDOI
Renal cell carcinoma.
James J. Hsieh,Mark P. Purdue,Sabina Signoretti,Charles Swanton,Laurence Albiges,Manuela Schmidinger,Daniel Y. Heng,James Larkin,Vincenzo Ficarra +8 more
TL;DR: An overview of the biology of RCC, with a focus on ccRCC, as well as updates to complement the current clinical guidelines and an outline of potential future directions for RCC research and therapy are provided.
Journal ArticleDOI
Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy
Robert E. Schoen,Paul F. Pinsky,Joel L. Weissfeld,Lance A. Yokochi,Timothy R. Church,Adeyinka O. Laiyemo,Robert S. Bresalier,Gerald L. Andriole,Saundra S. Buys,E. David Crawford,Mona N. Fouad,Claudine Isaacs,Christine Cole Johnson,Douglas J. Reding,Barbara O'Brien,Danielle M. Carrick,Patrick Wright,Thomas L. Riley,Mark P. Purdue,Grant Izmirlian,Barnett S. Kramer,Anthony B. Miller,John K. Gohagan,Philip C. Prorok,Christine D. Berg +24 more
TL;DR: Screening with flexible sigmoidoscopy was associated with a significant decrease in colorectal-cancer incidence (in both the distal and proximal colon) and mortality (distal colon only).
Journal ArticleDOI
Interaction between tobacco and alcohol use and the risk of head and neck cancer: pooled analysis in the International Head and Neck Cancer Epidemiology Consortium.
Mia Hashibe,Paul Brennan,Shu Chun Chuang,Stefania Boccia,Xavier Castellsagué,Chu Chen,Maria Paula Curado,Luigino Dal Maso,Alexander W. Daudt,Eleonora Fabianova,Leticia Fernandez,Victor Wünsch-Filho,Silvia Franceschi,Richard B. Hayes,Rolando Herrero,Karl T. Kelsey,Karl T. Kelsey,Sergio Koifman,Carlo La Vecchia,Philip Lazarus,Fabio Levi,Juan Lence,Dana Mates,Elena Matos,Ana Maria Menezes,Michael D. McClean,Joshua E. Muscat,José Eluf-Neto,Andrew F. Olshan,Mark P. Purdue,Peter Rudnai,Stephen M. Schwartz,Elaine M. Smith,Erich M. Sturgis,Neonilia Szeszenia-Dabrowska,Renato Talamini,Qingyi Wei,Deborah M. Winn,Oxana Shangina,Agnieszka Pilarska,Zuo-Feng Zhang,Gilles Ferro,Julien Berthiller,Paolo Boffetta +43 more
TL;DR: It is confirmed that the joint effect between tobacco and alcohol use is greater than multiplicative on head and neck cancer risk, however, a substantial proportion of head and head cancers cannot be attributed to tobacco or alcohol use, particularly for oral cavity cancer and for head andneck cancer among women and among young-onset cases.
Journal ArticleDOI
Genome-wide association study of circulating vitamin D levels
Jiyoung Ahn,Kai Yu,Rachael Z. Stolzenberg-Solomon,K. Claire Simon,Marjorie L. McCullough,Lisa Gallicchio,Eric J. Jacobs,Alberto Ascherio,Kathy J. Helzlsouer,Kevin B. Jacobs,Qizhai Li,Stephanie J. Weinstein,Mark P. Purdue,Jarmo Virtamo,Ronald L. Horst,William Wheeler,Stephen J. Chanock,David J. Hunter,Richard B. Hayes,Peter Kraft,Demetrius Albanes +20 more
TL;DR: Strong genome-wide significant associations with 25(OH)D are confirmed through meta-analysis with the GWAS data for GC, NADSYN1/DHCR7, CYP2R1 and CYP 2R1, but not C10orf88, the key C-25 hydroxylase that converts vitamin D3 to an active vitamin D receptor ligand.
Journal ArticleDOI
Detectable clonal mosaicism and its relationship to aging and cancer
Kevin B. Jacobs,Kevin B. Jacobs,Meredith Yeager,Meredith Yeager,Weiyin Zhou,Weiyin Zhou,Sholom Wacholder,Zhaoming Wang,Zhaoming Wang,Benjamín Rodríguez-Santiago,Amy Hutchinson,Amy Hutchinson,Xiang Deng,Xiang Deng,Chenwei Liu,Chenwei Liu,Marie Josephe Horner,Michael Cullen,Michael Cullen,Caroline G. Epstein,Laurie Burdett,Laurie Burdett,Michael Dean,Nilanjan Chatterjee,Joshua N. Sampson,Charles C. Chung,Joseph Kovaks,Susan M. Gapstur,Victoria L. Stevens,Lauren T. Teras,Mia M. Gaudet,Demetrius Albanes,Stephanie J. Weinstein,Jarmo Virtamo,Philip R. Taylor,Neal D. Freedman,Christian C. Abnet,Alisa M. Goldstein,Nan Hu,Kai Yu,Jian-Min Yuan,Jian-Min Yuan,Linda M. Liao,Ti Ding,You-Lin Qiao,Yu Tang Gao,Woon-Puay Koh,Yong-Bing Xiang,Ze Zhong Tang,Jin-Hu Fan,Melinda C. Aldrich,Christopher I. Amos,William J. Blot,Cathryn H. Bock,Elizabeth M. Gillanders,Curtis C. Harris,Christopher A. Haiman,Brian E. Henderson,Laurence N. Kolonel,Loic Le Marchand,Lorna H. McNeill,Benjamin A. Rybicki,Ann G. Schwartz,Lisa B. Signorello,Margaret R. Spitz,John K. Wiencke,Margaret Wrensch,Xifeng Wu,Krista A. Zanetti,Regina G. Ziegler,Jonine D. Figueroa,Montserrat Garcia-Closas,Núria Malats,Gaëlle Marenne,Ludmila Prokunina-Olsson,Dalsu Baris,Molly Schwenn,Alison Johnson,Maria Teresa Landi,Lynn R. Goldin,Dario Consonni,Pier Alberto Bertazzi,Melissa Rotunno,Preetha Rajaraman,Ulrika Andersson,Laura E. Beane Freeman,Christine D. Berg,Julie E. Buring,Mary Ann Butler,Tania Carreón,Maria Feychting,Anders Ahlbom,J. Michael Gaziano,Graham G. Giles,Graham G. Giles,Göran Hallmans,Susan E. Hankinson,Patricia Hartge,Roger Henriksson,Roger Henriksson,Peter D. Inskip,Christoffer Johansen,Annelie Landgren,Roberta McKean-Cowdin,Dominique S. Michaud,Dominique S. Michaud,Beatrice Melin,Ulrike Peters,Ulrike Peters,Avima M. Ruder,Howard D. Sesso,Gianluca Severi,Gianluca Severi,Xiao-Ou Shu,Kala Visvanathan,Emily White,Emily White,Alicja Wolk,Anne Zeleniuch-Jacquotte,Wei Zheng,Debra T. Silverman,Manolis Kogevinas,Juan R. González,Olaya Villa,Donghui Li,Eric J. Duell,Harvey A. Risch,Sara H. Olson,Charles Kooperberg,Brian M. Wolpin,Li Jiao,Manal M. Hassan,William Wheeler,Alan A. Arslan,H. Bas Bueno-de-Mesquita,Charles S. Fuchs,Steven Gallinger,Myron D. Gross,Elizabeth A. Holly,Alison P. Klein,Andrea Z. LaCroix,Margaret T. Mandelson,Margaret T. Mandelson,Gloria M. Petersen,Marie-Christine Boutron-Ruault,Paige M. Bracci,Federico Canzian,Kenneth J. Chang,Michelle Cotterchio,Edward Giovannucci,Michael Goggins,Judith A. Hoffman Bolton,Mazda Jenab,Kay-Tee Khaw,Vittorio Krogh,Robert C. Kurtz,Robert R. McWilliams,Julie B. Mendelsohn,Kari G. Rabe,Elio Riboli,Anne Tjønneland,Geoffrey S. Tobias,Dimitrios Trichopoulos,Dimitrios Trichopoulos,Joanne W. Elena,Herbert Yu,Laufey T. Amundadottir,Rachael Z. Stolzenberg-Solomon,Peter Kraft,Fredrick R. Schumacher,Daniel O. Stram,Sharon A. Savage,Lisa Mirabello,Irene L. Andrulis,Jay S. Wunder,Ana Patino Garcia,Luis Sierrasesà maga,Donald A. Barkauskas,Richard Gorlick,Mark P. Purdue,Wong Ho Chow,Lee E. Moore,Kendra Schwartz,Faith G. Davis,Ann W. Hsing,Sonja I. Berndt,Amanda Black,Nicolas Wentzensen,Louise A. Brinton,Jolanta Lissowska,Beata Peplonska,Katherine A. McGlynn,Michael B. Cook,Barry I. Graubard,Christian P. Kratz,Christian P. Kratz,Mark H. Greene,Ralph L. Erickson,David J. Hunter,Gilles Thomas,Robert N. Hoover,Francisco X. Real,Francisco X. Real,Joseph F. Fraumeni,Neil E. Caporaso,Margaret A. Tucker,Nathaniel Rothman,Luis A. Pérez-Jurado,Stephen J. Chanock +208 more
TL;DR: In an analysis of 31,717 cancer cases and 26,136 cancer-free controls from 13 genome-wide association studies, this paper observed large chromosomal abnormalities in a subset of clones in DNA obtained from blood or buccal samples.