Ramesh Rengan

TL;DR: Major tumour regressions are reported in a subset of patients with metastatic melanoma treated with an anti-CTLA4 antibody and radiation and reproduced this effect in mouse models, showing that PD-L1 on melanoma cells allows tumours to escape anti- NCTLA4-based therapy, and the combination of radiation, anti- CTLA4 and anti-PD-L 1 promotes response and immunity through distinct mechanisms.

TL;DR: This joint ESTRO-ASTRO practice recommendation established pragmatic and balanced consensus recommendations in common clinical scenarios of radiotherapy for lung cancer in order to address the challenges of the COVID-19 pandemic.

TL;DR: Kovoltage x-ray matching to bony anatomy is inadequate for accurate positioning when a conventional 3-5 mm margin is employed prior to lung SBRT, and CBCT image guidance with a 5-mm planning target volume margin is recommended.

TL;DR: This consensus report can be used to guide clinical practice and indications for PT, insurance approval, and clinical or translational research directions.

TL;DR: The results of this study provide population-based estimates for the incidence rates of patients with bone metastases at initial diagnosis of their solid tumor and can help clinicians to early detectBone metastases by bone screening to anticipate the occurrence of symptoms and favorably improve the prognosis.