R
Robert B. Innis
Researcher at National Institutes of Health
Publications - 468
Citations - 34412
Robert B. Innis is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Radioligand & Dopamine. The author has an hindex of 90, co-authored 455 publications receiving 32492 citations. Previous affiliations of Robert B. Innis include Yale University & Veterans Health Administration.
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Journal ArticleDOI
Consensus nomenclature for in vivo imaging of reversibly binding radioligands
Robert B. Innis,Vincent J. Cunningham,Jacques Delforge,Masahiro Fujita,Albert Gjedde,Roger N. Gunn,James E. Holden,Sylvain Houle,Sung-Cheng Huang,Masanori Ichise,Hidehiro Iida,Hiroshi Ito,Yuichi Kimura,Robert A. Koeppe,Gitte M. Knudsen,Juhani Knuuti,Adriaan A. Lammertsma,Marc Laruelle,Jean Logan,Ralph Paul Maguire,Mark A. Mintun,Evan D. Morris,Ramin V. Parsey,Julie C. Price,Mark Slifstein,Vesna Sossi,Tetsuya Suhara,John R. Votaw,Dean F. Wong,Richard E. Carson +29 more
TL;DR: An international group of experts in pharmacokinetic modeling recommends a consensus nomenclature to describe in vivo molecular imaging of reversibly binding radioligands.
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MRI-based measurement of hippocampal volume in patients with combat-related posttraumatic stress disorder.
J. Douglas Bremner,Penny Randall,Tammy Scott,Richard A. Bronen,John Seibyl,Steven M. Southwick,Richard C. Delaney,Gregory McCarthy,Dennis S. Charney,Robert B. Innis +9 more
TL;DR: A smaller right hippocampal volume in PTSD that is associated with functional deficits in verbal memory is consistent with high levels of cortisol associated with stress.
Journal ArticleDOI
Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects
Marc Laruelle,Anissa Abi-Dargham,C H van Dyck,Roberto Gil,Cyril D'Souza,Joseph Erdos,Elinore McCance,W Rosenblatt,Christine L Fingado,Sami S. Zoghbi,R. M. Baldwin,John Seibyl,John H. Krystal,Dennis S. Charney,Robert B. Innis +14 more
TL;DR: In the schizophrenic group, elevated amphetamine effect on [123I]IBZM binding potential was associated with emergence or worsening of positive psychotic symptoms, suggesting that psychotic symptoms elicited in this experimental setting in schizophrenia patients are associated with exaggerated stimulation of dopaminergic transmission.
Journal ArticleDOI
Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse--a preliminary report.
J. Douglas Bremner,Penny Randall,Penny Randall,Eric Vermetten,Lawrence H. Staib,Richard A. Bronen,Carolyn M. Mazure,Sandi Capelli,Gregory McCarthy,Gregory McCarthy,Robert B. Innis,Robert B. Innis,Dennis S. Charney,Dennis S. Charney +13 more
TL;DR: It is suggested that a decrease in left hippocampal volume is associated with abuse-related PTSD.
Journal ArticleDOI
Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort.
Anissa Abi-Dargham,Roberto Gil,John H. Krystal,R. M. Baldwin,John Seibyl,M. B. Bowers,van Dyck Ch,Dennis S. Charney,Robert B. Innis,Marc Laruelle +9 more
TL;DR: In this new cohort of subjects the authors replicated their initial observation of a dysregulation of striatal dopamine release in schizophrenia, with a significantly larger reduction in D2 receptor availability following acute amphetamine challenge than the comparison group.