R
Robert Tibshirani
Researcher at Stanford University
Publications - 620
Citations - 359457
Robert Tibshirani is an academic researcher from Stanford University. The author has contributed to research in topics: Lasso (statistics) & Gene expression profiling. The author has an hindex of 147, co-authored 593 publications receiving 326580 citations. Previous affiliations of Robert Tibshirani include University of Toronto & University of California.
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A Simple Method for Detecting Interactions between a Treatment and a Large Number of Covariates
TL;DR: It is shown that coupled with an efficiency augmentation procedure, this method produces clinically meaningful estimators in a variety of settings and can be useful for practicing personalized medicine: determining from a large set of biomarkers, the subset of patients that can potentially benefit from a treatment.
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A fast and scalable framework for large-scale and ultrahigh-dimensional sparse regression with application to the UK Biobank
Junyang Qian,Yosuke Tanigawa,Wenfei Du,Matthew Aguirre,Christopher C. Chang,Robert Tibshirani,Manuel A. Rivas,Trevor Hastie +7 more
TL;DR: A computational framework called batch screening iterative lasso (BASIL) that can take advantage of any existing lasso solver and easily build a scalable solution for very large data, including those that are larger than the memory size is proposed.
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Origins and clonal convergence of gastrointestinal IgE+ B cells in human peanut allergy
Ramona A. Hoh,Shilpa A. Joshi,Ji-Yeun Lee,Brock A. Martin,Sushama Varma,Shirley Kwok,Sandra C. A. Nielsen,Parastu Nejad,Emily Haraguchi,Priya S. Dixit,Swetha V. Shutthanandan,Krishna M. Roskin,Krishna M. Roskin,Wenming Zhang,Dana Tupa,Bryan J. Bunning,Monali Manohar,Robert Tibshirani,Nielsen Fernandez-Becker,Neeraja Kambham,Robert B. West,Robert G. Hamilton,Mindy Tsai,Stephen J. Galli,Rebecca S. Chinthrajah,Kari C. Nadeau,Scott D. Boyd +26 more
TL;DR: The gastrointestinal tract is defined as a reservoir of IgE+ B lineage cells in food allergy, as high-throughput DNA analysis indicated tissues were the sites of local isotype switching, and similar antibody sequences for the Ara h 2 peanut allergen were shared between patients.
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Gene expression profiling differentiates germ cell tumors from other cancers and defines subtype-specific signatures
Dejan Juric,Sanja Sale,Robert Hromas,Ron Yu,Yan Wang,George E. Duran,Robert Tibshirani,Lawrence H. Einhorn,Branimir I. Sikic +8 more
TL;DR: Dynamic computation of interaction networks and mapping to existing pathways knowledge databases revealed a potential role of EGR1 in p21-induced cell cycle arrest and intrinsic chemotherapy resistance of mature teratomas.
The delve manual
Carl Edward Rasmussen,Radford M. Neal,Geoffrey E. Hinton,D Van Camp,Michael Revow,Zoubin Ghahramani,Rafal Kustra,Robert Tibshirani +7 more
TL;DR: This manual describes the preliminary release of the DELVE environment, and recommends that you exercise caution when using this version of DELVE for real work, as it is possible that bugs remain in the software.