R
Roderic Guigó
Researcher at Pompeu Fabra University
Publications - 475
Citations - 121421
Roderic Guigó is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Computer science & Gene. The author has an hindex of 108, co-authored 304 publications receiving 106914 citations. Previous affiliations of Roderic Guigó include University of Barcelona & Harvard University.
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Journal ArticleDOI
M1683 Persistent Effect of Antibiotics On the Intestinal Microbiota
Chaysavanh Manichanh,Prudence Gibert,Marta Llopis,Encarna Varela,María Antolín,Roderic Guigó,Francisco Guarner +6 more
Posted ContentDOI
A transcriptional program shared across lineages underlies cell differentiation during metazoan development
Marina Ruiz-Romero,Cecilia C. Klein,Sílvia Pérez-Lluch,Amaya Abad,Alessandra Breschi,Roderic Guigó +5 more
TL;DR: The authors' data provides a novel perspective to metazoan development, and strongly suggest a model, in which the main transcriptional drive during cell type and tissue differentiation is the transition from precursor undifferentiated to terminally differentiated cells, irrespective of cell type.
Journal ArticleDOI
Corrigendum: Domains of genome-wide gene expression dysregulation in Down's syndrome.
Audrey Letourneau,Federico Santoni,Ximena Bonilla,M. Reza Sailani,David Gonzalez,Jop Kind,Claire Chevalier,Robert E. Thurman,Richard Sandstrom,Youssef Hibaoui,Marco Garieri,Konstantin Popadin,Emilie Falconnet,Maryline Gagnebin,Corinne Gehrig,Anne Vannier,Michel Guipponi,Laurent Farinelli,Daniel Robyr,Eugenia Migliavacca,Christelle Borel,Samuel Deutsch,Anis Feki,John A. Stamatoyannopoulos,Yann Herault,Bas van Steensel,Roderic Guigó,Stylianos E. Antonarakis +27 more
TL;DR: This corrects the article to show that the method used to derive the H2O2 “spatially aggregating force” is based on a two-step process, not a single step, like in the previous version of this paper.
Journal ArticleDOI
Functional Evolution of Clustered Aquaporin Genes Reveals Insights into the Oceanic Success of Teleost Eggs
Alba Ferré,François Chauvigné,Anna Vlasova,Birgitta Norberg,Luca Bargelloni,Roderic Guigó,Roderick Nigel Finn,Joan Cerdà +7 more
TL;DR: In this article , a previously unknown teleost-specific aquaporin-1 cluster (TSA1C) comprised of tandemly arranged aqp1aa-aqp1ab2-aq p1ab1 genes was uncovered, and a two-step regulated channel shunt avoids competitive occupancy of the same plasma membrane space in the oocyte and accelerates hydration.
Posted ContentDOI
A fast non-parametric test of association for multiple traits
TL;DR: This work derives the limiting null distribution of the PERMANOVA test statistic, providing a framework for the fast computation of asymptotic p values, and shows that the asymPTotic test presents controlled type I error and high power, comparable to or higher than parametric approaches.