Roderic Guigó

TL;DR: It is shown that blocking of ribosomal elongation results in stabilization of many associated lncRNAs, suggesting that the ribosome is the default destination for the majority of cytoplasmic long noncoding RNAs and may play a role in their degradation.

TL;DR: A notable difference is revealed in the prediction accuracy of expression levels of transcription start sites (TSSs) captured by different technologies and RNA extraction protocols, which implies that these features regulate transcription in a highly coordinated manner.

TL;DR: In this article, the aging gene expression signatures are very tissue specific and enrichment for some well-known aging components such as mitochondria biology is observed in many tissues, and different levels of cross-tissue synchronization of age-related gene expression changes are observed, and some essential tissues (e.g., heart and lung) show much stronger "co-aging" than other tissues based on principal component analysis.

TL;DR: The genome and transcriptome data generated for a Mesoamerican genotype represent a counterpart to the genomic resources already available for the Andean gene pool, and will allow the genetic dissection of the characters involved in the domestication and adaptation of the crop, and their further implementation in breeding strategies.

TL;DR: In this paper, the authors presented a computational study to detect functional RNA structures within the ENCODE regions of the human genome using three recently introduced programs based on either phylogenetic-stochastic context-free grammar (EvoFold) or energy directed folding (RNAz and AlifoldZ), yielding several thousand candidate structures.