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Christelle Borel

Researcher at University of Geneva

Publications -  79
Citations -  7466

Christelle Borel is an academic researcher from University of Geneva. The author has contributed to research in topics: Gene & Regulation of gene expression. The author has an hindex of 38, co-authored 75 publications receiving 6736 citations. Previous affiliations of Christelle Borel include French Institute of Health and Medical Research & Icahn School of Medicine at Mount Sinai.

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Journal ArticleDOI

A User's Guide to the Encyclopedia of DNA Elements (ENCODE)

Richard M. Myers, +328 more
- 01 Apr 2011 - 
TL;DR: An overview of the project and the resources it is generating and the application of ENCODE data to interpret the human genome are provided.
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Common Regulatory Variation Impacts Gene Expression in a Cell Type–Dependent Manner

Antigone S. Dimas, +15 more
- 04 Sep 2009 - 
TL;DR: The data suggest that the complete regulatory variant repertoire can only be uncovered in the context of cell-type specificity, and identifies multiple expressive quantitative trait loci per gene, unique or shared among cell types and positively correlated with the number of transcripts per gene.
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Genetic structure of Europeans: a view from the North-East

Mari Nelis, +48 more
- 08 May 2009 - 
TL;DR: This analysis revealed that the genetic structure of the European population correlates closely with geography, and allows the creation of a comprehensive European genetic map that will greatly facilitate inter-population genetic studies including genome wide association studies (GWAS).
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Passive and active DNA methylation and the interplay with genetic variation in gene regulation

Maria Gutierrez-Arcelus, +31 more
- 04 Jun 2013 - 
TL;DR: It is shown that unlike genetic regulatory variation, DNA methylation alone does not significantly drive allele specific expression, and inferred mechanistic relationships using genetic variation as well as correlations with TF abundance reveal both a passive and active role of DNAmethylation to regulatory interactions influencing gene expression.
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Human microRNA-155 on Chromosome 21 Differentially Interacts with Its Polymorphic Target in the AGTR1 3′ Untranslated Region: A Mechanism for Functional Single-Nucleotide Polymorphisms Related to Phenotypes

Praveen Sethupathy, +7 more
- 01 Aug 2007 - 
TL;DR: The 1166C allele may be functionally associated with hypertension by abrogating regulation by hsa-miR-155, thereby elevating AGTR1 levels, and mapping annotated SNPs onto a collection of experimentally supported human miRNA targets found one of these target sites containing SNP rs5186.