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Roderic Guigó
Researcher at Pompeu Fabra University
Publications - 475
Citations - 121421
Roderic Guigó is an academic researcher from Pompeu Fabra University. The author has contributed to research in topics: Computer science & Gene. The author has an hindex of 108, co-authored 304 publications receiving 106914 citations. Previous affiliations of Roderic Guigó include University of Barcelona & Harvard University.
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Journal ArticleDOI
Unweaving the Meanings of Messenger RNA Sequences
TL;DR: In addition to protein-coding information, mRNAs harbor regulatory sequences necessary for appropriate processing of their precursors and the diversity of these signals and the rules by which they function is explored.
Posted ContentDOI
The discovery potential of RNA processing profiles
TL;DR: SeRPeNT is developed, the first unsupervised computational method that exploits reproducibility across replicates and uses dynamic time-warping and density-based clustering algorithms to identify, characterize and compare small non-coding RNAs (sncRNAs) by harnessing the power of read profiles.
Posted ContentDOI
A limited set of transcriptional programs define major histological types and provide the molecular basis for a cellular taxonomy of the human body
Alessandra Breschi,Alessandra Breschi,Manuel Muñoz-Aguirre,Valentin Wucher,Carrie A. Davis,Diego Garrido-Martín,Sarah Djebali,Sarah Djebali,Jesse Gillis,Dmitri D. Pervouchine,Anna Vlasova,Alexander Dobin,Chris Zaleski,Jorg Drenkow,Cassidy Danyko,Alexandra Scavelli,Ferran Reverter,Michael Snyder,Thomas R. Gingeras,Roderic Guigó +19 more
TL;DR: RNA sequencing data for a number of primary cells from ten human body locations indicates that many cells in the human body belong to five major cell types of similar transcriptional complexity, and identifies genes whose expression is specific to these cell types.
Journal ArticleDOI
Correction: Corrigendum: Reproducibility of high-throughput mRNA and small RNA sequencing across laboratories
Peter A C 't Hoen,Marc R. Friedländer,Jonas Carlsson Almlöf,Michael Sammeth,Irina Pulyakhina,Seyed Yahya Anvar,Jeroen F. J. Laros,Henk P. J. Buermans,Olof Karlberg,Mathias Brännvall,Johan T. den Dunnen,Gert-Jan B. van Ommen,Ivo Gut,Roderic Guigó,Xavier Estivill,Ann-Christine Syvänen,Emmanouil T. Dermitzakis,Tuuli Lappalainen +17 more
TL;DR: In the version of this article initially published, in the list of members of the GEUVADIS consortium, Stylianos E Antonorakis should have been Stylians E Antonarakis.
Journal ArticleDOI
Brain transcriptomic profiling reveals common alterations across neurodegenerative and psychiatric disorders
TL;DR: In this paper , the authors examined transcriptome-wide characterization of eight conditions, using a total of 2,633 post-mortem brain samples from patients with Alzheimer's disease, Parkinson's disease (AD), progressive Supranuclear Palsy (PSP), Pathological Aging (PA), Autism Spectrum Disorder (ASD), Schizophrenia (Scz), Major Depressive Disorder (MDD), and Bipolar Disorder (BP).