Roderic Guigó

TL;DR: The authors summarize the data produced by phase III of the Encyclopedia of DNA Elements (ENCODE) project, a resource for better understanding of the human and mouse genomes, which have produced 5,992 new experimental datasets, including systematic determinations across mouse fetal development.

TL;DR: A genome-wide association analysis in the UK Biobank and INTERVAL studies is performed, providing evidence of shared genetic pathways linking blood cell indices with complex pathologies, including autoimmune diseases, schizophrenia, and coronary heart disease and evidence suggesting previously reported population associations betweenBlood cell indices and cardiovascular disease may be non-causal.

TL;DR: This analysis shows that high throughput sequencing technologies reveal new properties of Genetic effects on the transcriptome and allow the exploration of genetic effects in cellular processes.

TL;DR: The results indicated that the predictive accuracy of the programs analyzed was lower than originally found, which indicates that the programs are overly dependent on the particularities of the examples they learn from.

TL;DR: It is shown that in the unicellular eukaryote Paramecium tetraurelia, a ciliate, most of the nearly 40,000 genes arose through at least three successive whole-genome duplications.