Ronald Klein

TL;DR: A systematic review and an individual-participant meta-analysis of population-based cohort studies, adjusting for traditional risk factors, to determine the associations between retinal vessel caliber and CHD risk and examined whether the associations differed between women and men.

TL;DR: In the youngest age groups who were at risk for developing early or late age-related ARM, higher levels of lutein and zeaxanthin in the diet were related to lower odds for pigmentary abnormalities, one sign of early ARM.

TL;DR: The relation of hyperglycemia to the long-term incidence and progression of diabetic retinopathy, gross proteinuria, end-stage renal disease, and history of neuropathy in persons with either IDDM or NIDDM is examined using data from a large, population-based study, the Wisconsin Epidemiologic Study of Diabetic Retinopathy (WESDR).

TL;DR: There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies, and inclusion of retinal Venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.

TL;DR: Retinal arteriolar and venular diameters narrow with increasing age, and these parameters are inversely related to BP, independent of age, gender, and smoking.