R
Ronald Klein
Researcher at University of Wisconsin-Madison
Publications - 1306
Citations - 163459
Ronald Klein is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Population & Diabetes mellitus. The author has an hindex of 194, co-authored 1305 publications receiving 149140 citations. Previous affiliations of Ronald Klein include Los Angeles Biomedical Research Institute & Wake Forest University.
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Journal ArticleDOI
Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?
Rajkumar Dorajoo,Ruoying Li,Mohammad Kamran Ikram,Jianjun Liu,Philippe Froguel,Philippe Froguel,Jeannette Lee,Xueling Sim,Xueling Sim,Rick Twee-Hee Ong,Wan Ting Tay,Chen Peng,Terri L. Young,Terri L. Young,Alexandra I. F. Blakemore,Ching-Yu Cheng,Tin Aung,Paul Mitchell,Jie Jin Wang,Jie Jin Wang,Caroline C W Klaver,Eric Boerwinkle,Ronald Klein,David S. Siscovick,Richard A. Jensen,Vilmundur Gudnason,Albert V. Smith,Yik Ying Teo,Tien Yin Wong,Tien Yin Wong,E-Shyong Tai,Chew-Kiat Heng,Yechiel Friedlander +32 more
TL;DR: Common variants associated with serum CRP, first detected in primarily European studies, are also associated with CRP levels in East-Asian and South-Asian populations and a causal link between CRP and retinal measures of microvascular disease is found.
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Ten-year incidence of self-reported erectile dysfunction in people with long-term type 1 diabetes.
TL;DR: It is suggested that cessation of cigarette smoking and tighter control of blood pressure might prevent or delay the onset of erectile dysfunction in persons with type 1 diabetes.
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Age-Related Macular Degeneration and Incident Cardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis
Antonio B. Fernandez,Tien Yin Wong,Ronald Klein,Dorothea Collins,Gregory L. Burke,Mary Frances Cotch,Barbara E.K. Klein,Mehran M. Sadeghi,Jersey Chen +8 more
TL;DR: In persons without a history of CVD, AMD was not associated with an increased risk of CHD or CVD and in Cox regression models adjusting for CVD risk factors, there was no significant relationship between presence of any AMD and any CHD/CVD events.
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Exome array analysis identifies CAV1/CAV2 as a susceptibility locus for intraocular pressure.
Fei Chen,Alison P. Klein,Barbara E.K. Klein,Kristine E. Lee,Barbara Truitt,Ronald Klein,Sudha K. Iyengar,Priya Duggal +7 more
TL;DR: The results suggest that novel genetic variants and genes with multiple, less common variants may play a role in the control of IOP, and the implication of the caveolin genes, CAV1/CAV2, as a common genetic factor influencing both IOP variations and POAG may provide new insights of the underlying mechanism leading to glaucoma and glAUcomatous visual field loss.
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Serum cystatin C and the incidence of type 2 diabetes mellitus
TL;DR: These findings show a positive relationship of serum cystatin C levels with the incidence of type 2 diabetes mellitus independently of confounding risk factors, and strongly suggest the need for further evaluation of the potential importance of cyStatin C in the pathogenesis of type 1 Diabetes mellitus.