R
Ronald Klein
Researcher at University of Wisconsin-Madison
Publications - 1306
Citations - 163459
Ronald Klein is an academic researcher from University of Wisconsin-Madison. The author has contributed to research in topics: Population & Diabetes mellitus. The author has an hindex of 194, co-authored 1305 publications receiving 149140 citations. Previous affiliations of Ronald Klein include Los Angeles Biomedical Research Institute & Wake Forest University.
Papers
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Journal ArticleDOI
Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins
Ronald Klein,Robert D. Dayton,Nancy J. Leidenheimer,Karen Jansen,Todd E. Golde,Richard M. Zweig +5 more
TL;DR: The efficient AAV8 is promising for animal models of neurodegenerative diseases and potentially as well for gene therapy of brain diseases, although the toxicity observed with GFP expression warrants great caution.
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Fructosamine and glycated albumin for risk stratification and prediction of incident diabetes and microvascular complications: a prospective cohort analysis of the Atherosclerosis Risk in Communities (ARIC) study
Elizabeth Selvin,Andreea M. Rawlings,Morgan E. Grams,Ronald Klein,A. Richey Sharrett,Michael W Steffes,Josef Coresh +6 more
TL;DR: Fructosamine and glycated albumin were strongly associated with incident diabetes and its microvascular complications, with prognostic value comparable to HbA1c, but Hb a1c outperformed fructosamines and glycations for prediction of incident diabetes with C statistics of 0·760, 0·706, and 0·703, respectively.
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Pathogenesis of lesions in late age-related macular disease.
TL;DR: There is increasing understanding concerning the sequence of events that lead to those lesions causing loss of central vision in AMD, and therapeutic approaches that address the underlying mechanisms are more likely to succeed than current treatment options.
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Association of NIDDM and Hearing Loss
TL;DR: Data from population-based longitudinal studies of aging conducted in Beaver Dam, Wisconsin, are suggestive of a weak association between NIDDM and hearing loss.
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Prevalence of diabetes mellitus in southern wisconsin
TL;DR: The prevalence of known cases of diabetes was ascertained from patient records in an 11-county area in Wisconsin in July 1979 to June 1980 to be 1%, and males had higher age-adjusted rates than females.