Ronald Klein

TL;DR: The prevalence of age-related maculopathy varies considerably in different locations and racial/ethnic groups around the world as discussed by the authors, and there are insufficient data to determine whether it is likely that these differences in prevalence, especially for the early forms of ARM are due to variations in genetic and environmental factors or due to differences in age of the cohorts and methods used to ascertain and define ARM.

TL;DR: In vivo somatic gene transfer methodology using AAV is reviewed, finding advantageous features of this system include neuronal gene expression that is: (1) efficient; (2) long-lived; and (3) non-toxic.

TL;DR: Evidence for a major ARMD locus on 15q21, which, coupled with numerous other loci segregating in these families, suggests complex oligogenic patterns of inheritance for ARMD.

TL;DR: It is indicated that cataract surgery is a relatively frequent occurrence in people with diabetes, and this finding needs to be considered to plan for health care for people with Diabetes.

TL;DR: Findings indicate a relationship between cataract surgery and increased risk of progression of age-related maculopathy.