R
Roy R. Chaudhuri
Researcher at University of Sheffield
Publications - 88
Citations - 5777
Roy R. Chaudhuri is an academic researcher from University of Sheffield. The author has contributed to research in topics: Gene & Virulence. The author has an hindex of 36, co-authored 84 publications receiving 5272 citations. Previous affiliations of Roy R. Chaudhuri include University of Nottingham & Gartnavel General Hospital.
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Journal ArticleDOI
The Pangenome Structure of Escherichia coli: Comparative Genomic Analysis of E. coli Commensal and Pathogenic Isolates
David A. Rasko,M. J. Rosovitz,Garry S. A. Myers,Emmanuel F. Mongodin,W. Florian Fricke,Pawel Gajer,Jonathan Crabtree,Mohammed Sebaihia,Nicholas R. Thomson,Roy R. Chaudhuri,Ian R. Henderson,Vanessa Sperandio,Jacques Ravel +12 more
TL;DR: Pangenomic calculations indicate that E. coli genomic diversity represents an open pangenome model containing a reservoir of more than 13,000 genes, many of which may be uncharacterized but important virulence factors, which should provide the basis for future functional work on this important group of pathogens.
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Escherichia coli K-12: a cooperatively developed annotation snapshot—2005
Monica Riley,Takashi Abe,Martha B. Arnaud,Mary B. Berlyn,Frederick R. Blattner,Roy R. Chaudhuri,Jeremy D. Glasner,Takashi Horiuchi,Ingrid M. Keseler,Takehide Kosuge,Hirotada Mori,Hirotada Mori,Nicole T. Perna,Guy Plunkett,Kenneth E. Rudd,Margrethe H. Serres,Gavin H. Thomas,Nicholas R. Thomson,David S. Wishart,Barry L. Wanner +19 more
TL;DR: A snapshot analysis based on the most recent genome sequences of two E.coli K-12 strains allows comparison of their genotypes and mutant status of alleles.
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The origins of acquired immune deficiency syndrome viruses: where and when?
Paul M. Sharp,Elizabeth Bailes,Roy R. Chaudhuri,Cynthia M. Rodenburg,Mario O. Santiago,Beatrice H. Hahn +5 more
TL;DR: The inferred geographical origin of HIV-1 and the timing of the cross-species transmission are inconsistent with the suggestion that oral polio vaccines, putatively contaminated with viruses from chimpanzees in eastern equatorial Africa in the late 1950s, could be responsible for the origin of acquired immune deficiency syndrome.
Journal ArticleDOI
Comprehensive identification of essential Staphylococcus aureus genes using Transposon-Mediated Differential Hybridisation (TMDH)
Roy R. Chaudhuri,Andrew G. Allen,Paul J. Owen,Gil Shalom,Karl Stone,Marcus Harrison,Timothy A. Burgis,Michael Lockyer,Jorge Garcia-Lara,Simon J. Foster,Stephen J. Pleasance,Sarah Peters,Duncan J. Maskell,Ian G. Charles +13 more
TL;DR: A robust microarray and PCR-based method, Transposon-Mediated Differential Hybridisation (TMDH), that uses novel bioinformatics to identify transposon inserts in genome-wide libraries is developed and determined the first comprehensive list of S. aureus essential genes.
Journal ArticleDOI
Genomic analysis of secretion systems
TL;DR: Interestingly, genomic analyses have also hinted at the existence of a dedicated protein secretion system in Gram-positive bacteria, targeting members of the WXG100/ESAT-6 family of proteins, and have revealed an unexpectedly wide distribution of sortase-driven protein-targeting systems.