Rudolph Bohm

TL;DR: In this article, the authors demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain displayed on an I53-50 protein nanoparticle scaffold (hereafter designated RBD-NP), to stimulate robust and durable neutralizing-antibody responses.

TL;DR: It is suggested that priming by vaccination of B cell anti-HIV envelope responses maybe crucial for the long-term control of HIV infection.

TL;DR: It is concluded that peripheral destructive processes, rather than a loss of thymic output, appear to be the main causes of T cell depletion in SIV infection.

TL;DR: The ability of C274 to stimulate B cells and DCs in healthy and infected monkeys suggests its possible use as a broad‐acting adjuvant to be applied in the rhesus macaque model for the development of preventative and therapeutic vaccines.

TL;DR: Minimally invasive thoracoscopic surgical techniques can be used successfully to collect thymic tissue from adult and juvenile rhesus monkeys with minimal surgical morbidity.