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Meera Trisal
Researcher at Stanford University
Publications - 4
Citations - 463
Meera Trisal is an academic researcher from Stanford University. The author has contributed to research in topics: Vaccination & Immunity. The author has an hindex of 3, co-authored 4 publications receiving 76 citations.
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Journal ArticleDOI
Systems vaccinology of the BNT162b2 mRNA vaccine in humans.
Prabhu S. Arunachalam,Madeleine K D Scott,Thomas Hagan,Thomas Hagan,Chunfeng Li,Yupeng Feng,Florian Wimmers,Lilit Grigoryan,Meera Trisal,Venkata Viswanadh Edara,Lilin Lai,Sarah Esther Chang,Allan Feng,Shaurya Dhingra,Mihir Shah,Alexandra S. Lee,Sharon Chinthrajah,Sayantani B. Sindher,Vamsee Mallajosyula,Fei Gao,Natalia Sigal,Sangeeta Kowli,Sheena Gupta,Kathryn L. Pellegrini,Gregory K. Tharp,Sofia Maysel-Auslender,Sydney Hamilton,Hadj Aoued,Kevin Hrusovsky,Mark Roskey,Steven E. Bosinger,Steven E. Bosinger,Holden T. Maecker,Scott D. Boyd,Mark M. Davis,Paul J. Utz,Mehul S. Suthar,Purvesh Khatri,Kari C. Nadeau,Kari C. Nadeau,Bali Pulendran +40 more
TL;DR: In this article, the authors used a system vaccinology approach to comprehensively profile the innate and adaptive immune responses of 56 healthy volunteers who were vaccinated with the Pfizer-BioNTech mRNA vaccine (BNT162b2).
Journal ArticleDOI
Adjuvanting a subunit COVID-19 vaccine to induce protective immunity.
Prabhu S. Arunachalam,Alexandra C. Walls,Nadia A. Golden,Caroline Atyeo,Stephanie Fischinger,Chunfeng Li,Pyone P. Aye,Mary Jane Navarro,Lilin Lai,Venkata Viswanadh Edara,Katharina Röltgen,Kenneth A. Rogers,Lisa Shirreff,Douglas E. Ferrell,Samuel Wrenn,Deleah Pettie,John C. Kraft,Marcos C. Miranda,Elizabeth Kepl,Claire Sydeman,Natalie Brunette,Michael E. P. Murphy,Brooke Fiala,Lauren Carter,Alexander G. White,Meera Trisal,Ching-Lin Hsieh,Kasi E. Russell-Lodrigue,Christopher Monjure,Jason Dufour,Skye Spencer,Lara A. Doyle-Meyers,Rudolph Bohm,Nicholas J. Maness,Chad J. Roy,Jessica A. Plante,Kenneth S. Plante,Alex Lee Zhu,Matthew J. Gorman,Sally Shin,Xiaoying Shen,Jane Fontenot,Shakti Gupta,Derek T. O'Hagan,Robbert van der Most,Rino Rappuoli,Robert L. Coffman,David Novack,Jason S. McLellan,Shankar Subramaniam,David C. Montefiori,Scott D. Boyd,JoAnne L. Flynn,Galit Alter,Francois Villinger,Harry Kleanthous,Jay Rappaport,Mehul S. Suthar,Neil P. King,Neil P. King,David Veesler,Bali Pulendran +61 more
TL;DR: In this article, the authors demonstrate the capacity of a subunit vaccine, comprising the SARS-CoV-2 spike protein receptor-binding domain displayed on an I53-50 protein nanoparticle scaffold (hereafter designated RBD-NP), to stimulate robust and durable neutralizing-antibody responses.
Posted ContentDOI
Durability of immune responses to the BNT162b2 mRNA vaccine
Mehul S. Suthar,Prabhu S. Arunachalam,Mengyun Hu,Noah Reis,Meera Trisal,Olivia Raeber,Sharon Chinthrajah,Meredith E. Davis-Gardner,Kelly Manning,Prakriti Mudvari,Sucheta Godbole,Eli Boritz,Amy R. Henry,Daniel C. Douek,Kari C. Nadeau,Yoshihiro Kawaoka,Yoshihiro Kawaoka,Veronika I. Zarnitsyna,Bali Pulendran,Peter Halfmann +19 more
TL;DR: The authors reported a substantial waning of antibody responses and T cell immunity to SARS-CoV-2 and its variants, at 6 months following the second immunization with the BNT162b2 vaccine.
Posted ContentDOI
Adjuvanting a subunit SARS-CoV-2 nanoparticle vaccine to induce protective immunity in non-human primates
Prabhu S. Arunachalam,Alexandra C. Walls,Nadia A. Golden,Caroline Atyeo,Stephanie Fischinger,Chunfeng Li,Pyone P. Aye,Mary Jane Navarro,Lilin Lai,Venkata Viswanadh Edara,Katharina Röltgen,Kenneth A. Rogers,Lisa Shirreff,Douglas E. Ferrell,Samuel Wrenn,Deleah Pettie,John C. Kraft,Marcos C. Miranda,Elizabeth Kepl,Claire Sydeman,Natalie Brunette,Michael E. P. Murphy,Brooke Fiala,Lauren Carter,Alexander G. White,Meera Trisal,Ching-Lin Hsieh,Kasi E. Russell-Lodrigue,Christopher Monjure,Jason Dufour,Lara Doyle-Meyer,Rudolph B Bohm,Nicholas J. Maness,Chad J. Roy,Jessica A. Plante,Kenneth S. Plante,Alex Lee Zhu,Matthew J. Gorman,Sally Shin,Xiaoying Shen,Jane Fontenot,Shakti Gupta,Derek T O Hagan,Robbert van der Most,Rino Rappuoli,Robert L Coffman,David Novack,Jason S. McLellan,Shankar Subramaniam,David C. Montefiori,Scott D. Boyd,JoAnne L. Flynn,Galit Alter,Francois Villinger,Harry Kleanthous,Jay Rappaport,Mehul S. Suthar,Neil P. King,Neil P. King,David Veesler,Bali Pulendran +60 more
TL;DR: In this paper, the authors demonstrate the capacity of a subunit vaccine under clinical development, comprising the SARS-CoV-2 Spike protein receptor-binding domain displayed on a two-component protein nanoparticle (RBD-NP), to stimulate robust and durable neutralizing antibody (nAb) responses and protection against SARS CoV2 in non-human primates.