D
David W. Clark
Researcher at University of Edinburgh
Publications - 25
Citations - 3615
David W. Clark is an academic researcher from University of Edinburgh. The author has contributed to research in topics: Genome-wide association study & Population. The author has an hindex of 11, co-authored 22 publications receiving 2158 citations.
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Journal ArticleDOI
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
James J. Lee,Robbee Wedow,Aysu Okbay,Edward Kong,Omeed Maghzian,Meghan Zacher,Tuan Anh Nguyen-Viet,Peter Bowers,Julia Sidorenko,Julia Sidorenko,Richard Karlsson Linnér,Richard Karlsson Linnér,Mark Alan Fontana,Mark Alan Fontana,Tushar Kundu,Chanwook Lee,Hui Li,Ruoxi Li,Rebecca Royer,Pascal Timshel,Pascal Timshel,Raymond K. Walters,Raymond K. Walters,Emily A. Willoughby,Loic Yengo,Maris Alver,Yanchun Bao,David W. Clark,Felix R. Day,Nicholas A. Furlotte,Peter K. Joshi,Peter K. Joshi,Kathryn E. Kemper,Aaron Kleinman,Claudia Langenberg,Reedik Mägi,Joey W. Trampush,Shefali S. Verma,Yang Wu,Max Lam,Jing Hua Zhao,Zhili Zheng,Zhili Zheng,Jason D. Boardman,Harry Campbell,Jeremy Freese,Kathleen Mullan Harris,Caroline Hayward,Pamela Herd,Pamela Herd,Meena Kumari,Todd Lencz,Todd Lencz,Jian'an Luan,Anil K. Malhotra,Anil K. Malhotra,Andres Metspalu,Lili Milani,Ken K. Ong,John R. B. Perry,David J. Porteous,Marylyn D. Ritchie,Melissa C. Smart,Blair H. Smith,Joyce Y. Tung,Nicholas J. Wareham,James F. Wilson,Jonathan P. Beauchamp,Dalton Conley,Tõnu Esko,Steven F. Lehrer,Steven F. Lehrer,Steven F. Lehrer,Patrik K. E. Magnusson,Sven Oskarsson,Tune H. Pers,Tune H. Pers,Matthew R. Robinson,Matthew R. Robinson,Kevin Thom,Chelsea Watson,Christopher F. Chabris,Michelle N. Meyer,David Laibson,Jian Yang,Magnus Johannesson,Philipp Koellinger,Philipp Koellinger,Patrick Turley,Patrick Turley,Peter M. Visscher,Daniel J. Benjamin,Daniel J. Benjamin,David Cesarini,David Cesarini +94 more
TL;DR: A joint (multi-phenotype) analysis of educational attainment and three related cognitive phenotypes generates polygenic scores that explain 11–13% of the variance ineducational attainment and 7–10% ofthe variance in cognitive performance, which substantially increases the utility ofpolygenic scores as tools in research.
Journal ArticleDOI
Runs of homozygosity: windows into population history and trait architecture.
TL;DR: How to identify ROH in genome-wide microarray and sequence data, their distribution in human populations and their application to the understanding of inbreeding depression and disease risk are discussed.
Journal ArticleDOI
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Richard Karlsson Linnér,Richard Karlsson Linnér,Pietro Biroli,Edward Kong,S. Fleur W. Meddens,S. Fleur W. Meddens,Robbee Wedow,Mark Alan Fontana,Mark Alan Fontana,Maël Lebreton,Stephen P. Tino,Abdel Abdellaoui,Anke R. Hammerschlag,Michel G. Nivard,Aysu Okbay,Cornelius A. Rietveld,Pascal Timshel,Pascal Timshel,Maciej Trzaskowski,Ronald de Vlaming,Ronald de Vlaming,Christian L. Zund,Yanchun Bao,Laura Buzdugan,Laura Buzdugan,Ann H. Caplin,Chia-Yen Chen,Chia-Yen Chen,Peter Eibich,Peter Eibich,Peter Eibich,Pierre Fontanillas,Juan R. González,Peter K. Joshi,Ville Karhunen,Aaron Kleinman,Remy Z. Levin,Christina M. Lill,Gerardus A. Meddens,Gerard Muntané,Gerard Muntané,Sandra Sanchez-Roige,Frank J. A. van Rooij,Erdogan Taskesen,Yang Wu,Futao Zhang,Adam Auton,Jason D. Boardman,David W. Clark,Andrew Conlin,Conor C. Dolan,Urs Fischbacher,Patrick J. F. Groenen,Kathleen Mullan Harris,Gregor Hasler,Albert Hofman,Albert Hofman,Mohammad Arfan Ikram,Sonia Jain,Robert Karlsson,Ronald C. Kessler,Maarten Kooyman,James MacKillop,James MacKillop,Minna Männikkö,Carlos Morcillo-Suarez,Matthew B. McQueen,Klaus M. Schmidt,Melissa C. Smart,Matthias Sutter,Matthias Sutter,Matthias Sutter,Roy Thurik,André G. Uitterlinden,Jon White,Harriet de Wit,Jian Yang,Lars Bertram,Lars Bertram,Dorret I. Boomsma,Tõnu Esko,Ernst Fehr,David A. Hinds,Magnus Johannesson,Meena Kumari,David Laibson,Patrik K. E. Magnusson,Michelle N. Meyer,Arcadi Navarro,Arcadi Navarro,Abraham A. Palmer,Tune H. Pers,Tune H. Pers,Danielle Posthuma,Daniel Schunk,Murray B. Stein,Rauli Svento,Henning Tiemeier,Paul R. H. J. Timmers,Patrick Turley,Patrick Turley,Patrick Turley,Robert J. Ursano,Gert G. Wagner,Gert G. Wagner,James F. Wilson,James F. Wilson,Jacob Gratten,Jacob Gratten,James J. Lee,David Cesarini,Daniel J. Benjamin,Daniel J. Benjamin,Philipp Koellinger,Philipp Koellinger,Jonathan P. Beauchamp +115 more
TL;DR: This paper found evidence of substantial shared genetic influences across risk tolerance and the risky behaviors: 46 of the 99 general risk tolerance loci contain a lead SNP for at least one of their other GWAS, and general risk-tolerance is genetically correlated with a range of risky behaviors.
Journal ArticleDOI
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Rachael A. Evans,Hamish McAuley,Ewen M Harrison,Aarti Shikotra,Amisha Singapuri,Marco Sereno,Omer Elneima,Annemarie B Docherty,Nazir I Lone,Nazir I Lone,Olivia C. Leavy,Luke Daines,J Kenneth Baillie,J Kenneth Baillie,Jeremy S. Brown,Trudie Chalder,Anthony De Soyza,Nawar Diar Bakerly,Nawar Diar Bakerly,Nicholas Easom,John R. Geddes,John R. Geddes,Neil J. Greening,Nicholas Hart,Liam G Heaney,Liam G Heaney,Simon Heller,Luke Howard,John R. Hurst,Joseph Jacob,R. Gisli Jenkins,Caroline J. Jolley,Steven Kerr,Onn Min Kon,Onn Min Kon,Keir Lewis,Janet M. Lord,Gerry P McCann,Stefan Neubauer,Peter J. M. Openshaw,Dhruv Parekh,Dhruv Parekh,Paul E Pfeffer,Paul E Pfeffer,Najib M. Rahman,Betty Raman,Matthew Richardson,Matthew J. Rowland,Malcolm G Semple,Malcolm G Semple,Ajay M. Shah,Sally J Singh,Aziz Sheikh,David B. Thomas,Mark Toshner,James D. Chalmers,Ling-Pei Ho,Alex Horsley,Michael Marks,Michael Marks,Krisnah Poinasamy,Louise V. Wain,Christopher E. Brightling,Kathryn M. Abel,Huzaifa Adamali,Davies Adeloye,O Adeyemi,F Adeyemi,S Ahmad,R Ahmed,M Ainsworth,A Alamoudi,M Aljaroof,Louise Allan,R Allen,A Alli,B Al-Sheklly,D Altmann,Denise Anderson,M Andrews,A Angyal,Charalambos Antoniades,Gill Arbane,Cherie Armour,N Armstrong,Lynne Armstrong,H Arnold,David T Arnold,Milton Ashworth,A Ashworth,H Assefa-Kebede,P Atkin,H Atkins,A Atkins,R Aul,C Avram,R Baggott,D Baguley,J K Baillie,S Bain,M Bakali,M Bakau,Emma Baldry,David R Baldwin,Clive Ballard,J Bambrough,Ruth E Barker,Shaney L Barratt,F Barrett,N Basu,Rachel L. Batterham,H Baxendale,Hannah Bayes,M Bayley,Michael Beadsworth,P Beirne,R Bell,Derek Bell,Colin Berry,S Betts,K Bhui,L Bishop,J Blaikely,C Bloomfield,A Bloss,A Bolger,C E Bolton,J Bonnington,A Botkai,M Bourne,C Bourne,E Bradley,K Bramham,L Brear,Gerome Breen,J Breeze,A Briggs,E Bright,C E Brightling,Simon E. Brill,K Brindle,L Broad,M Broome,J S Brown,Matthew A. Brown,Jamie Brown,Richard G. Brown,V Brown,Ashley C. Brown,Traolach S. Brugha,Nigel J. Brunskill,M Buch,A Bularga,Edward T. Bullmore,David J. Burn,G Burns,Jonathan P. Busby,A.J. Buttress,S Byrne,P Cairns,P C Calder,E Calvelo,B Card,L Carr,Gail Carson,Patrice Carter,J Cavanagh,T Chalder,J D Chalmers,Rachel C. Chambers,Keith M. Channon,Kath Chapman,A Charalambou,N Chaudhuri,A Checkley,J Chen,L Chetham,E R Chilvers,H Chinoy,K Chong-James,N Choudhury,G Choudhury,P Chowdhury,P Chowienczyk,C Christie,David W. Clark,C. Clark,Judith Clarke,P Clift,Sara Clohisey,Z Coburn,John B. Cole,C Coleman,D W Connell,B Connolly,Lynda Connor,Angela Cook,Brendan G Cooper,C Coupland,T Craig,P Crisp,D. Cristiano,M G Crooks,A Cross,I Cruz,Paul Cullinan,L Daines,M Dalton,Paul Dark,J. Dasgin,Asaf David,C David,Melanie J. Davies,Gail Davies,Kevin A. Davies,F. Davies,G A Davies,Enya Daynes,T I de Silva,A De Soyza,Bill Deakin,A Deans,S Defres,Anne Dell,K Dempsey,Joe Dennis,A Dewar,R Dharmagunawardena,N Diar Bakerly,A Dipper,S Diver,S N Diwanji,M Dixon,R Djukanovic,H Dobson,C Dobson,S L Dobson,A B Docherty,Andrew Donaldson,T Dong,N. Dormand,A Dougherty,R Dowling,S Drain,P Dulawan,S Dunn,N Easom,C Echevarria,Sebastian Edwards,Charlotte L. Edwardson,B Elliott,Amanda F. Elliott,Y Ellis,A Elmer,O Elneima,R A Evans,Julie Evans,H Evans,David M. Evans,R I Evans,R Evans,Todd Evans,L Fabbri,S Fairbairn,A Fairman,K Fallon,D Faluyi,C Favager,Timothy Felton,Jonathan Finch,S Finney,Helen L. Fisher,Shelley Fletcher,R Flockton,D Foote,A Ford,D Forton,Richard W. Francis,S Francis,C Francis,A Frankel,E Fraser,R Free,N French,J Fuld,James J Furniss,L Garner,Nikki Gautam,J R Geddes,P M George,Jeremy George,M Gibbons,L Gilmour,Fergus V. Gleeson,J Glossop,S Glover,N Goodman,B Gooptu,T. Gorsuch,E Gourlay,P Greenhaff,William Greenhalf,A Greenhalgh,N J Greening,John P Greenwood,S Greenwood,R Gregory,Douglas Grieve,M. Gummadi,Atul Gupta,S Gurram,Ellen Guthrie,K Hadley,A Haggar,K Hainey,P Haldar,I Hall,Lynsey S. Hall,M Halling-Brown,R Hamil,N A Hanley,Hayley Hardwick,Elaine Hardy,B Hargadon,Kyle Harrington,V Harris,E M Harrison,Phil Harrison,N Hart,Alison G. Harvey,Miriam Harvey,M Harvie,M Havinden-Williams,J Hawkes,N Hawkings,J Haworth,A Hayday,L G Heaney,J L Heeney,Melissa Heightman,S Heller,Morag Henderson,L Hesselden,Toby Hillman,Aroon D. Hingorani,T Hiwot,L P Ho,A Hoare,M Hoare,P Hogarth,A Holbourn,L Holdsworth,D Holgate,K Holmes,B Holroyd-Hind,A Horsley,A Hosseini,Matthew Hotopf,L Houchen,Louise M. Howard,A Howell,E Hufton,Alan Hughes,Joseph Hughes,R Hughes,A Humphries,N Huneke,J R Hurst,R Hurst,Mujtaba Husain,T Hussell,W Ibrahim,A Ient,L Ingram,Khalida Ismail,Thomas A Jackson,J Jacob,W Y James,Sam M. Janes,H Jarvis,B Jayaraman,R G Jenkins,Peter Jezzard,K Jiwa,Sonia Johnson,Craig Johnson,D Johnston,C Jolley,C J Jolley,Ifan Jones,S Jones,D Jones,H Jones,Graeme Jones,Margaret Jones,S. Jose,Thomas Kabir,G Kaltsakas,Vicky Kamwa,P Kar,Z Kausar,Siobhan Kelly,S Kerr,A L Key,F Khan,Kamlesh Khunti,C King,B King,P Kitterick,Paul Klenerman,L Knibbs,Stephen R Knight,A Knighton,O M Kon,S Kon,S S Kon,Ania Korszun,Christos P Kotanidis,I Koychev,P Kurupati,J Kwan,C Laing,H Lamlum,Geraldine Landers,Claudia Langenberg,Daniel Lasserson,Alison M. Lawrie,A Lea,O C Leavy,Donghyung Lee,E Lee,K Leitch,R Lenagh,K Lewis,V Lewis,K E Lewis,J Lewis,N Lewis-Burke,Teresa Light,L Lightstone,L Lim,S Linford,A Lingford-Hughes,Marc Lipman,K. Liyanage,A Lloyd,S Logan,David A. Lomas,N I Lone,R. Loosley,J M Lord,H Lota,A Lucey,G MacGowan,I Macharia,Clare E. Mackay,Linda MacLiver,Shyam Madathil,G Madzamba,N Magee,N Mairs,N Majeed,E Major,M Malim,G Mallison,W Man,Swapna Mandal,K Mangion,P Mansoori,S Marciniak,M Mariveles,M Marks,Ben G. Marshall,A Martineau,Nick A Maskell,D Matila,L Matthews,J Mayet,S McAdoo,H McAllister-Williams,P McArdle,A McArdle,D McAulay,H McAuley,Daniel F. McAuley,K McCafferty,G P McCann,H McCauley,P McCourt,L Mcgarvey,J McGinness,A McGovern,H. McGuinness,Iain B. McInnes,K McIvor,E McIvor,Alex D. McMahon,M J McMahon,L. McMorrow,T Mcnally,M McNarry,A McQueen,Helen McShane,S Megson,J Meiring,Donna J. Menzies,A Michael,L Milligan,N Mills,James E. Mitchell,A Mohamed,Philip L. Molyneaux,William Monteiro,A Morley,L Morrison,R Morriss,Ardythe L. Morrow,A Moss,A J Moss,Paul Moss,Elizabeta B. Mukaetova-Ladinska,U Munawar,Elodie Murali,J Murira,H Nassa,P Neill,S Neubauer,David E. Newby,H Newell,A Newton Cox,Timothy R Nicholson,D Nicoll,Claire M. Nolan,M J Noonan,P. Novotny,J Nunag,J Nyaboko,L. O'Brien,N Odell,G Ogg,O Olaosebikan,C Oliver,Z. Omar,Peter J. M. Openshaw,P Rivera-Ortega,R Osbourne,Marlies Ostermann,C Overton,J Oxton,E Pacpaco,S Paddick,Padmasayee Papineni,K Paradowski,M Pareek,D Parekh,H Parfrey,Carmine M. Pariante,Stephen C. J. Parker,Margot W. Parkes,J Parmar,R Parvin,S Patale,Brij Patel,Smitaa Patel,Meenal Patel,B Pathmanathan,Michael Pavlides,J E Pearl,Daniel Peckham,J. Pendlebury,Y Peng,Catherine Pennington,I Peralta,E. Perkins,T Peto,Nayia Petousi,John R. Petrie,P Pfeffer,J Phipps,Jonathan Pimm,K Piper Hanley,R Pius,S Plein,T Plekhanova,K Poinasamy,Oliver Polgar,L Poll,J C Porter,S Portukhay,N Powell,L Price,David Price,Anthony N. Price,C. Price,A Prickett,S. Quaid,J Quigley,Jennifer K Quint,H Qureshi,N Rahman,M Rahman,M Ralser,B Raman,A Ramos,J Rangeley,Tim Rees,K Regan,Alexander Richards,M Richardson,E Robertson,J Rodgers,G Ross,J Rossdale,Anthony J. Rostron,A Routen,A Rowland,M J Rowland,J Rowland,S L Rowland-Jones,K Roy,Igor Rudan,R Russell,E. Russell,R Sabit,E K Sage,Nilesh J. Samani,R Samuel,E Sapey,D Saralaya,A Saratzis,Jack A. Sargeant,T Sass,Naveed Sattar,Kathryn J Saunders,R Saunders,W Saxon,Avan Aihie Sayer,W Schwaeble,Janet T Scott,K Scott,N Selby,Malcolm G Semple,M Sereno,Khalid Shah,A. J. Shah,P Shah,Manu Sharma,Michael Sharpe,C Sharpe,V Shaw,A Sheikh,K Shevket,A Shikotra,Jennifer M. Short,Salman Siddiqui,Louise Sigfrid,G Simons,J Simpson,A Singapuri,S J Singh,C Singh,S Singh,J Skeemer,I Smith,Jennifer A. Smith,Lee B. Smith,Andrew Smith,Marcia Soares,D Southern,M Spears,L G Spencer,F Speranza,Louise Stadon,S Stanel,Michael C Steiner,David J. Stensel,M Stern,Isobel D. Stewart,James Stockley,Richard Kevin Stone,A Storrie,K Storton,E Stringer,Christian P Subbe,Cathie Sudlow,Z Suleiman,Charlotte Summers,C Summersgill,D Sutherland,D L Sykes,Robert Sykes,Nick P. Talbot,A L Tan,Clare J Taylor,Andrew M. Taylor,A Te,H Tedd,C J Tee,H. Tench,S Terry,S Thackray-Nocera,F Thaivalappil,D Thickett,David C. Thomas,D C Thomas,Aliki Thomas,Alfred A.R. Thompson,Teresa Thompson,T Thornton,Ryan S Thwaites,Mark J. Tobin,G F Toingson,C Tong,M Toshner,Rhian M. Touyz,K A Tripp,Elizabeth M. Tunnicliffe,E Turner,L Turtle,H Turton,R Ugwuoke,R Upthegrove,J Valabhji,K Vellore,E Wade,L V Wain,L O Wajero,S Walder,Susan P. Walker,E Wall,T Wallis,S Walmsley,S Walsh,Jill Walsh,L Watson,JM Watson,E. Watson,Carly Welch,H Welch,B. Welsh,Simon Wessely,S West,H Wheeler,V Whitehead,J Whitney,S Whittaker,B Whittam,J Wild,M Wilkins,D Wilkinson,Nicola Williams,Bryan Williams,Julie Williams,S A Williams-Howard,M Willicombe,G Willis,David Wilson,I Wilson,N Window,Miles D. Witham,R. Wolf-Roberts,F Woodhead,J Woods,Daniel G. Wootton,J Worsley,D Wraith,L Wright,C Wright,S Wright,C Xie,S Yasmin,Thomas Yates,K P Yip,B Young,S Young,A Young,A J Yousuf,A Yousuf,A Zawia,B Zhao,O. Zongo +780 more
TL;DR: In this paper, the effects of COVID-19-related hospitalisation on health and employment, to identify factors associated with recovery, and to describe recovery phenotypes were determined.
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Richard Karlsson Linnér,Pietro Biroli,Edward Kong,Fleur Meddens,Robbee Wedow,Mark Alan Fontana,Mael Lebreton,Stephen P. Tino,Abdel Abdellaoui,Anke R. Hammerschlag,Michel G. Nivard,Aysu Okbay,Cornelius A. Rietveld,Pascal N. Timshel,Maciej Trzaskowski,Ronald de Vlaming,Christian L. Zund,Yanchun Bao,Laura Buzdugan,Ann H. Caplin,Chia-Yen Chen,Peter Eibich,Pierre Fontanillas,Juan R. González,Peter K. Joshi,Ville Karhunen,Aaron Kleinman,Remy Z. Levin,Christina M. Lill,Gerardus A. Meddens,Gerard Muntané,Sandra Sanchez-Roige,Frank J. A. van Rooij,Erdogan Taskesen,Yang Wu,Futao Zhang,Michelle Agee,Babak Alipanahi,Robert K. Bell,Katarzyna Bryc,Sarah L. Elson,Nicholas A. Furlotte,Karen E. Huber,Nadia K. Litterman,Jennifer C. McCreight,Matthew H. McIntyre,Joanna L. Mountain,Carrie A.M. Northover,Steven J. Pitts,J. Fah Sathirapongsasuti,Olga V. Sazonova,Janie F. Shelton,Suyash Shringarpure,Chao Tian,Joyce Y. Tung,Vladimir Vacic,Catherine H. Wilson,Mawusse Agbessi,Habibul Ahsan,Isabel Alves,Anand Kumar Andiappan,Philip Awadalla,Alexis Battle,Frank Beutner,Marc Jan Bonder,Dorret I. Boomsma,Mark W. Christiansen,Annique Claringbould,Patrick Deelen,Tõnu Esko,Marie-Julie Favé,Lude Franke,Timothy M. Frayling,Sina A. Gharib,Gregory Gibson,Bastiaan T. Heijmans,Gibran Hemani,Rick Jansen,Mika Kähönen,Anette Kalnapenkis,Silva Kasela,Johannes Kettunen,Yungil Kim,Holger Kirsten,Peter Kovacs,Knut Krohn,Jaanika Kronberg-Guzman,Viktorija Kukushkina,Zoltán Kutalik,Bernett Lee,Terho Lehtimäki,Markus Loeffler,Urko M. Marigorta,Andres Metspalu,Lili Milani,Grant W. Montgomery,Martina Mueller-Nurasyid,Matthias Nauck,Brenda W.J.H. Penninx,Markus Perola,Natalia Pervjakova,Brandon L. Pierce,Joseph E. Powell,Holger Prokisch,Bruce M. Psaty,Olli T. Raitakari,Susan M. Ring,Samuli Ripatti,Olaf Rotzchke,Sina Rüeger,Ashis Saha,Markus Scholz,Katharina Schramm,Ilkka Seppälä,Michael Stumvoll,Patrick Sullivan,Peter-Bramt Hoen,Alexander Teumer,Joachim Thiery,Lin Tong,Anke Tönjes,Jenny van Dongen,Joyce B. J. van Meurs,Joost Verlouw,Peter M. Visscher,Uwe Voelker,Urmo Võsa,Harm-Jan Westra,Hanieh Yaghootkar,Jian Yang,Biao Zeng,James J. Lee,Tune H. Pers,Patrick Turley,Guo-Bo Chen,Valur Emilsson,Sven Oskarsson,Joseph K. Pickrell,Kevin Thom,Pascal Timshel,Tarunveer S. Ahluwalia,Jonas Bacelis,Clemens Baumbach,Gyda Bjornsdottir,Johannes H. Brandsma,Maria Pina Concas,Jaime Derringer,Tessel E. Galesloot,Giorgia Girotto,Richa Gupta,Leanne M. Hall,Sarah E. Harris,Edith Hofer,Momoko Horikoshi,Jennifer E. Huffman,Kadri Kaasik,Ioanna P. Kalafati,Augustine Kong,Jari Lahti,Sven J. van der Lee,Christiaan de Leeuw,Penelope A. Lind,Karl-Oskar Lindgren,Tian Liu,Massimo Mangino,Jonathan Marten,Evelin Mihailov,Michael B. Miller,Peter J. van der Most,Christopher Oldmeadow,Antony Payton,Wouter J. Peyrot,Yong Qian,Rico Rueedi,Erika Salvi,Boerge Schmidt,Katharina E. Schraut,Jianxin Shi,Albert V. Smith,Raymond A. Poot,Beate St Pourcain,Gudmar Thorleifsson,Niek Verweij,Dragana Vuckovic,Juergen Wellmann,Jingyun Yang,Wei Zhao,Zhihong Zhu,Behrooz Z. Alizadeh,Najaf Amin,Andrew Bakshi,Sebastian E. Baumeister,Ginevra Biino,Klaus Bønnelykke,Patricia A. Boyle,Harry Campbell,Francesco P. Cappuccio,Gail Davies,Jan-Emmanuel De Neve,Panos Deloukas,Ilja Demuth,Jun Ding,Lewin Eisele,Niina Eklund,David M. Evans,Jessica D. Faul,Mary F. Feitosa,Andreas J. Forstner,Ilaria Gandin,Bjarni Gunnarsson,Bjarni V. Halldorsson,Tamara B. Harris,Andrew Heath,Lynne J. Hocking,Elizabeth G. Holliday,Georg Homuth,Michael A. Horan,Jouke-Jan Hottenga,Philip L. De Jager,Astanand Jugessur,Marika Kaakinen,Stavroula Kanoni,Liisa Keltigangas-Jarvinen,Lambertus A. Kiemeney,Ivana Kolcic,Seppo Koskinen,Aldi T. Kraja,Martin Kroh,Antti Latvala,Lenore J. Launer,Maël Lebreton,Douglas F. Levinson,Paul Lichtenstein,Peter Lichtner,David C. Liewald,Anu Loukola,Pamela A. F. Madden,Reedik Mägi,Tomi Mäki-Opas,Riccardo E. Marioni,Pedro Marques-Vidal,George McMahon,Christa Meisinger,Thomas Meitinger,Y. Milaneschi,Ronny Myhre,Christopher P. Nelson,Dale R. Nyholt,William E R Ollier,Aarno Palotie,Lavinia Paternoster,Nancy L. Pedersen,K. Petrovic,David J. Porteous,Katri Räikkönen,S M Ring,Antonietta Robino,Olga Rostapshova,Igor Rudan,Aldo Rustichini,Veikko Salomaa,Alan R. Sanders,Antti-Pekka Sarin,Helena Schmidt,Rodney J. Scott,Blair H. Smith,Jennifer A. Smith,Jan A. Staessen,Elisabeth Steinhagen-Thiessen,Konstantin Strauch,Antonio Terracciano,Martin D. Tobin,Sheila Ulivi,Simona Vaccargiu,Lydia Quaye,Cristina Venturini,Anna A. E. Vinkhuyzen,Henry Voelzke,Judith M. Vonk,Diego Vozzi,Johannes Waage,Erin B. Ware,Gonneke Willemsen,John Attia,David A. Bennett,Klaus Berger,Lars Bertram,Hans Bisgaard,Ingrid B. Borecki,Ute Bültmann,Christopher F. Chabris,Francesco Cucca,Daniele Cusi,J. Deary,George Dedoussis,Cornelia M. van Duijn,Johan G. Eriksson,Barbara Franke,Paolo Gasparini,Pablo V. Gejman,Christian Gieger,Hans-Joergen Grabe,Jacob Gratten,Vilmundur Gudnason,Pim van der Harst,Caroline Hayward,David A. Hinds,Wolfgang Hoffmann,Elina Hyppönen,William G. Iacono,Bo Jacobsson,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Jaakko Kaprio,Sharon L.R. Kardia,Steven F. Lehrer,Patrik K. E. Magnusson,Nicholas G. Martin,Matt McGue,Neil Pendleton,Nicola Pirastu,Mario Pirastu,Ozren Polasek,Danielle Posthuma,Christine Power,Michael A. Province,Nilesh J. Samani,David Schlessinger,Reinhold E. Schmidt,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Unnur Thorsteinsdottir,Roy Thurik,Nicholas J. Timpson,Henning Tiemeier,André G. Uitterlinden,Veronique Vitart,Peter Vollenweider,David R. Weir,James F. Wilson,Alan F. Wright,Dalton Conley,Robert F. Krueger,George Davey Smith,David Laibson,Sarah E. Medland,Magnus Johannesson,Philipp Koellinger,David Cesarini,Daniel J. Benjamin,Adam Auton,Jason D. Boardman,David W. Clark,Andrew Conlin,Conor C. Dolan,Urs Fischbacher,Patrick J. F. Groenen,Kathleen Mullan Harris,Gregor Hasler,Albert Hofman,Mohammad Arfan Ikram,Sonia Jain,Robert Karlsson,Ronald C. Kessler,Maarten Kooyman,James MacKillop,Minna Männikkö,Carlos Morcillo-Suarez,Matthew B. McQueen,Klaus M. Schmidt,Melissa C. Smart,Matthias Sutter,Jon White,Harriet de Wit,Ernst Fehr,Meena Kumari,David Laibson,Michelle N. Meyer,Arcadi Navarro,Abraham A. Palmer,Daniel Schunk,Murray B. Stein,Rauli Svento,Paul R. H. J. Timmers,Robert J. Ursano,Gert G. Wagner,Jonathan P. Beauchamp +387 more
TL;DR: A genetic study identifies hundreds of loci associated with risk tolerance and risky behaviors, finds evidence of substantial shared genetic influences across these phenotypes, and implicates genes involved in neurotransmission.