S
Sam J. Wilson
Researcher at University of Glasgow
Publications - 57
Citations - 6372
Sam J. Wilson is an academic researcher from University of Glasgow. The author has contributed to research in topics: Viral replication & Interferon. The author has an hindex of 24, co-authored 46 publications receiving 5302 citations. Previous affiliations of Sam J. Wilson include Howard Hughes Medical Institute & Rockefeller University.
Papers
More filters
Journal ArticleDOI
Barriers to Infection of Human Cells by Feline Leukemia Virus: Insights into Resistance to Zoonosis.
Anne Terry,Anna Kilbey,Asif Naseer,Laura S. Levy,Shamim Ahmad,Ciorsdaidh Watts,Nancy Mackay,Ewan R. Cameron,Sam J. Wilson,James C. Neil +9 more
TL;DR: It is found that blood cells are uniquely resistant to infection with FeLV-B due to the activity of cellular enzymes that mutate the viral genome.
Posted ContentDOI
Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early genes.
Chen-Hsuin Lee,Stephen Chiweshe,Dominique McCormick,Anna Raper,Arthur Wickenhagen,Victor R. DeFilippis,Eleanor Gaunt,Peter Simmonds,Sam J. Wilson,Finn Grey +9 more
TL;DR: It is demonstrated for the first time that ZAP is a potent host restriction factor against large DNA viruses and that HCMV evades ZAP detection through suppression of CpG dinucleotides within the major immediate early transcripts.
Posted ContentDOI
Insights into circovirus host range from the genomic fossil record.
Tristan P.W. Dennis,Peter J. Flynn,William Marciel de Souza,Joshua B Singer,Corrie S. Moreau,Sam J. Wilson,Robert J. Gifford +6 more
TL;DR: This study screened genome assemblies of 675 animal species and identified numerous circovirus-related sequences, including the first examples of CVe derived from cyclovirus, and confirmed the presence of these CVe in the germline of the elongate twig ant, thereby establishing that cycloviruses infect insects.
Posted ContentDOI
A Prenylated dsRNA Sensor Protects Against Severe COVID-19 and is Absent in Horseshoe Bats
Arthur Wickenhagen,Elena Sugrue,Spyros Lytras,Srikeerthana Kuchi,Matthew L. Turnbull,Colin Loney,Vanessa Herder,Jay Allan,Innes Jarmson,Natalia Cameron-Ruiz,Margus Varjak,Rute Maria Pinto,Douglas G. Stewart,Simon Swingler,Marko Noerenberg,Edward J. D. Greenwood,Thomas W M Crozier,Quan Gu,Sara Clohisey,Bo Wang,Fabio T. M. Costa,Monique Freire Santana,Luiz Carlos de Lima Ferreira,Isaric C-Investigators,Joao Luiz Da Silva Filho,Matthias Marti,Richard J. Stanton,Edward Chung Yern Wang,Alfredo Castello-Palomares,Antonia Ho,Kenneth Baillie,Ruth F. Jarrett,David Robertson,Massimo Palmarini,Paul J. Lehner,Suzannah J. Rihn,Sam J. Wilson +36 more
TL;DR: In this article, the authors used interferon-stimulated gene (ISG) expression screening to reveal that OAS1, through RNase L, potently inhibits SARS-CoV-2.
Journal ArticleDOI
Extreme genetic fragility of the HIV-1 capsid
Suzannah J. Rihn,Suzannah J. Rihn,Sam J. Wilson,Sam J. Wilson,Nicholas J. Loman,Mudathir Alim,Mudathir Alim,Saskia E. Bakker,David Bhella,Frazer J. Rixon,Paul D. Bieniasz,Paul D. Bieniasz +11 more
TL;DR: HIV-1 CA is found to be the most genetically fragile protein that has been analyzed using a library of single amino acid substitution mutants, and suggests that CA is a good target for therapy and vaccination strategies.