S
Scott Hennigan
Researcher at Massachusetts Department of Public Health
Publications - 9
Citations - 502
Scott Hennigan is an academic researcher from Massachusetts Department of Public Health. The author has contributed to research in topics: Metagenomics & Zika virus. The author has an hindex of 6, co-authored 9 publications receiving 399 citations.
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Journal ArticleDOI
Zika virus evolution and spread in the Americas
Hayden C. Metsky,Hayden C. Metsky,Christian B. Matranga,Shirlee Wohl,Shirlee Wohl,Stephen F. Schaffner,Stephen F. Schaffner,Catherine A. Freije,Catherine A. Freije,Sarah M. Winnicki,Kendra West,James Qu,Mary Lynn Baniecki,Adrianne Gladden-Young,Aaron E. Lin,Aaron E. Lin,Christopher Tomkins-Tinch,Simon Ye,Simon Ye,Daniel J. Park,Cynthia Y. Luo,Cynthia Y. Luo,Kayla G. Barnes,Kayla G. Barnes,Rickey R. Shah,Rickey R. Shah,Bridget Chak,Bridget Chak,Giselle Barbosa-Lima,Edson Delatorre,Yasmine Rangel Vieira,Lauren M. Paul,Amanda L Tan,Carolyn M. Barcellona,Mario C. Porcelli,Chalmers Vasquez,Andrew C. Cannons,Marshall R. Cone,Kelly N. Hogan,Edgar W. Kopp,Joshua J. Anzinger,Kimberly García,Leda Parham,Rosa Margarita Gelvez Ramirez,Maria Conseulo Miranda Montoya,Diana Patricia Rojas,Catherine M. Brown,Scott Hennigan,Brandon Sabina,Sarah Scotland,Karthik Gangavarapu,Nathan D. Grubaugh,Glenn Oliveira,Refugio Robles-Sikisaka,Andrew Rambaut,Andrew Rambaut,Lee Gehrke,Lee Gehrke,Sandra Smole,M. Elizabeth Halloran,M. Elizabeth Halloran,Luis Angel Villar,Salim Mattar,Ivette Lorenzana,José Cerbino-Neto,Clarissa Valim,Clarissa Valim,Wim Degrave,Patrícia T. Bozza,Andreas Gnirke,Kristian G. Andersen,Kristian G. Andersen,Sharon Isern,Scott F. Michael,Fernando A. Bozza,Thiago Moreno L. Souza,Irene Bosch,Nathan L. Yozwiak,Nathan L. Yozwiak,Bronwyn MacInnis,Bronwyn MacInnis,Pardis C. Sabeti +81 more
TL;DR: It is found that ZIKV circulated undetected in multiple regions for many months before the first locally transmitted cases were confirmed, highlighting the importance of surveillance of viral infections.
Journal ArticleDOI
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.
Hayden C. Metsky,Hayden C. Metsky,Katherine J. Siddle,Katherine J. Siddle,Adrianne Gladden-Young,James Qu,David K Yang,David K Yang,Patrick Brehio,Andrew Goldfarb,Anne Piantadosi,Anne Piantadosi,Shirlee Wohl,Shirlee Wohl,Amber Carter,Aaron E. Lin,Aaron E. Lin,Kayla G. Barnes,Kayla G. Barnes,Damien C. Tully,Bjӧrn Corleis,Scott Hennigan,Giselle Barbosa-Lima,Yasmine Rangel Vieira,Lauren M. Paul,Amanda L Tan,Kimberly García,Leda Parham,Ikponmwonsa Odia,Philomena Eromon,Onikepe A. Folarin,Onikepe A. Folarin,Augustine Goba,Etienne Simon-Loriere,Lisa E. Hensley,Angel Balmaseda,Eva Harris,Douglas S. Kwon,Douglas S. Kwon,Todd M. Allen,Jonathan A. Runstadler,Sandra Smole,Fernando A. Bozza,Thiago Moreno L. Souza,Sharon Isern,Scott F. Michael,Ivette Lorenzana,Lee Gehrke,Lee Gehrke,Irene Bosch,Gregory D. Ebel,Donald S. Grant,Christian T. Happi,Daniel J. Park,Andreas Gnirke,Pardis C. Sabeti,Christian B. Matranga +56 more
TL;DR: This work designs optimal probe sets, with a specified number of oligonucleotides, that achieve full coverage of, and scale well with, known sequence diversity, and applies them to capture viral genomes in complex metagenomic samples.
Journal ArticleDOI
Combining genomics and epidemiology to track mumps virus transmission in the United States.
Shirlee Wohl,Hayden C. Metsky,Hayden C. Metsky,Stephen F. Schaffner,Stephen F. Schaffner,Anne Piantadosi,Anne Piantadosi,Meagan Burns,Joseph A Lewnard,Bridget Chak,Bridget Chak,Lydia A. Krasilnikova,Lydia A. Krasilnikova,Katherine J. Siddle,Katherine J. Siddle,Christian B. Matranga,Bettina Bankamp,Scott Hennigan,Brandon Sabina,Elizabeth H. Byrne,Elizabeth H. Byrne,Rebecca J. McNall,Rickey R. Shah,Rickey R. Shah,James Qu,Daniel J. Park,Soheyla D. Gharib,Susan Fitzgerald,Paul J. Barreira,Stephen J. Fleming,Susan M. Lett,Paul A. Rota,Lawrence C. Madoff,Lawrence C. Madoff,Nathan L. Yozwiak,Nathan L. Yozwiak,Bronwyn MacInnis,Bronwyn MacInnis,Sandra Smole,Yonatan H. Grad,Pardis C. Sabeti +40 more
TL;DR: This analysis suggests continuous, undetected circulation of mumps locally and nationally, including multiple independent introductions into Massachusetts and into individual communities, and shows that one lineage has dominated in the US since at least 2006.
Journal ArticleDOI
Large-Scale Complete-Genome Sequencing and Phylodynamic Analysis of Eastern Equine Encephalitis Virus Reveals Source-Sink Transmission Dynamics in the United States.
Yi Tan,Yi Tan,Tommy Tsan-Yuk Lam,Lea Heberlein-Larson,Sandra Smole,Albert J. Auguste,Scott Hennigan,Rebecca A. Halpin,Nadia Fedorova,Vinita Puri,Timothy B. Stockwell,Meghan H. Shilts,Meghan H. Shilts,Theodore G. Andreadis,Philip M. Armstrong,Robert B. Tesh,Scott C. Weaver,Thomas R. Unnasch,Alexander T. Ciota,Alexander T. Ciota,Laura D. Kramer,Laura D. Kramer,Suman R. Das,Suman R. Das +23 more
TL;DR: This study comprehensively determined the evolution of the virus, described the epidemiological dynamics of EEEV in different states in the United States, and identified Florida as one of the major sources.
Journal ArticleDOI
Jamestown Canyon virus in Massachusetts: clinical case series and vector screening
Cormac M. Kinsella,Cormac M. Kinsella,Molly L Paras,Sandra Smole,Samar B. Mehta,Samar B. Mehta,Vijay S. Ganesh,Lin H. Chen,Lin H. Chen,Daniel P. McQuillen,Daniel P. McQuillen,Ruta Shah,Ruta Shah,Justin Chan,Matthew Osborne,Scott Hennigan,Frederic Halpern-Smith,Catherine M. Brown,Pardis C. Sabeti,Anne Piantadosi,Anne Piantadosi +20 more
TL;DR: Nine patients diagnosed with neuroinvasive JCV infection in Massachusetts from 2013, the year of the first reported case, to 2017 are described and an RT-qPCR assay is developed and evaluated for detection of JCV RNA.