I
Ivette Lorenzana
Researcher at Universidad Nacional Autónoma de Honduras
Publications - 27
Citations - 1522
Ivette Lorenzana is an academic researcher from Universidad Nacional Autónoma de Honduras. The author has contributed to research in topics: Zika virus & Alphavirus. The author has an hindex of 11, co-authored 26 publications receiving 1047 citations.
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Journal ArticleDOI
Field-deployable viral diagnostics using CRISPR-Cas13
Cameron Myhrvold,Cameron Myhrvold,Catherine A. Freije,Catherine A. Freije,Jonathan S. Gootenberg,Omar O. Abudayyeh,Hayden C. Metsky,Ann Durbin,Ann Durbin,Max J. Kellner,Amanda L Tan,Lauren M. Paul,Leda Parham,Kimberly García,Kayla G. Barnes,Kayla G. Barnes,Bridget Chak,Bridget Chak,Adriano Mondini,Maurício Lacerda Nogueira,Sharon Isern,Scott F. Michael,Ivette Lorenzana,Nathan L. Yozwiak,Nathan L. Yozwiak,Bronwyn MacInnis,Bronwyn MacInnis,Irene Bosch,Irene Bosch,Lee Gehrke,Lee Gehrke,Feng Zhang,Pardis C. Sabeti +32 more
TL;DR: The Cas13-based SHERLOCK platform can detect Zika virus and dengue virus in patient samples at concentrations as low as 1 copy per microliter and can distinguish the four DENV serotypes, as well as region-specific strains of ZIKV from the 2015–2016 pandemic.
Journal ArticleDOI
Zika virus evolution and spread in the Americas
Hayden C. Metsky,Hayden C. Metsky,Christian B. Matranga,Shirlee Wohl,Shirlee Wohl,Stephen F. Schaffner,Stephen F. Schaffner,Catherine A. Freije,Catherine A. Freije,Sarah M. Winnicki,Kendra West,James Qu,Mary Lynn Baniecki,Adrianne Gladden-Young,Aaron E. Lin,Aaron E. Lin,Christopher Tomkins-Tinch,Simon Ye,Simon Ye,Daniel J. Park,Cynthia Y. Luo,Cynthia Y. Luo,Kayla G. Barnes,Kayla G. Barnes,Rickey R. Shah,Rickey R. Shah,Bridget Chak,Bridget Chak,Giselle Barbosa-Lima,Edson Delatorre,Yasmine Rangel Vieira,Lauren M. Paul,Amanda L Tan,Carolyn M. Barcellona,Mario C. Porcelli,Chalmers Vasquez,Andrew C. Cannons,Marshall R. Cone,Kelly N. Hogan,Edgar W. Kopp,Joshua J. Anzinger,Kimberly García,Leda Parham,Rosa Margarita Gelvez Ramirez,Maria Conseulo Miranda Montoya,Diana Patricia Rojas,Catherine M. Brown,Scott Hennigan,Brandon Sabina,Sarah Scotland,Karthik Gangavarapu,Nathan D. Grubaugh,Glenn Oliveira,Refugio Robles-Sikisaka,Andrew Rambaut,Andrew Rambaut,Lee Gehrke,Lee Gehrke,Sandra Smole,M. Elizabeth Halloran,M. Elizabeth Halloran,Luis Angel Villar,Salim Mattar,Ivette Lorenzana,José Cerbino-Neto,Clarissa Valim,Clarissa Valim,Wim Degrave,Patrícia T. Bozza,Andreas Gnirke,Kristian G. Andersen,Kristian G. Andersen,Sharon Isern,Scott F. Michael,Fernando A. Bozza,Thiago Moreno L. Souza,Irene Bosch,Nathan L. Yozwiak,Nathan L. Yozwiak,Bronwyn MacInnis,Bronwyn MacInnis,Pardis C. Sabeti +81 more
TL;DR: It is found that ZIKV circulated undetected in multiple regions for many months before the first locally transmitted cases were confirmed, highlighting the importance of surveillance of viral infections.
Journal ArticleDOI
Capturing sequence diversity in metagenomes with comprehensive and scalable probe design.
Hayden C. Metsky,Hayden C. Metsky,Katherine J. Siddle,Katherine J. Siddle,Adrianne Gladden-Young,James Qu,David K Yang,David K Yang,Patrick Brehio,Andrew Goldfarb,Anne Piantadosi,Anne Piantadosi,Shirlee Wohl,Shirlee Wohl,Amber Carter,Aaron E. Lin,Aaron E. Lin,Kayla G. Barnes,Kayla G. Barnes,Damien C. Tully,Bjӧrn Corleis,Scott Hennigan,Giselle Barbosa-Lima,Yasmine Rangel Vieira,Lauren M. Paul,Amanda L Tan,Kimberly García,Leda Parham,Ikponmwonsa Odia,Philomena Eromon,Onikepe A. Folarin,Onikepe A. Folarin,Augustine Goba,Etienne Simon-Loriere,Lisa E. Hensley,Angel Balmaseda,Eva Harris,Douglas S. Kwon,Douglas S. Kwon,Todd M. Allen,Jonathan A. Runstadler,Sandra Smole,Fernando A. Bozza,Thiago Moreno L. Souza,Sharon Isern,Scott F. Michael,Ivette Lorenzana,Lee Gehrke,Lee Gehrke,Irene Bosch,Gregory D. Ebel,Donald S. Grant,Christian T. Happi,Daniel J. Park,Andreas Gnirke,Pardis C. Sabeti,Christian B. Matranga +56 more
TL;DR: This work designs optimal probe sets, with a specified number of oligonucleotides, that achieve full coverage of, and scale well with, known sequence diversity, and applies them to capture viral genomes in complex metagenomic samples.
Journal ArticleDOI
Zika virus associated with sensory polyneuropathy
Marco T. Medina,John D. England,Ivette Lorenzana,Marco Medina-Montoya,Diego Alvarado,Mario De Bastos,Santiago Fontiveros,Manuel Sierra,Francis Contreras +8 more
Journal ArticleDOI
Novel HLA class I associations with HIV-1 control in a unique genetically admixed population
Humberto Valenzuela-Ponce,Selma Alva-Hernández,Daniela Garrido-Rodríguez,Maribel Soto-Nava,Thalia Garcia-Tellez,Tania Escamilla-Gomez,Claudia García-Morales,Verónica S Quiroz-Morales,Daniela Tapia-Trejo,Silvia J Del Arenal-Sánchez,Francisco-Javier Prado-Galbarro,Ramón Hernández-Juan,Edna Rodríguez-Aguirre,Akio Murakami-Ogasawara,Carlos Mejía-Villatoro,Ingrid Y. Escobar-Urias,Rodolfo Pinzón-Meza,Juan Miguel Pascale,Yamitzel Zaldivar,Guillermo Porras-Cortés,Carlos Quant-Durán,Ivette Lorenzana,Rita I Meza,Elsa Palou,Marvin Manzanero,Rolando A Cedillos,Carmen Aláez,Mark A. Brockman,Mark A. Brockman,P. Richard Harrigan,Chanson J. Brumme,Zabrina L. Brumme,Zabrina L. Brumme,Santiago Ávila-Ríos,Gustavo Reyes-Terán +34 more
TL;DR: The identification of both canonical and novel HLA/HIV associations provides a first step towards improved understanding of HIV immune control among unique and understudied Mestizo populations.