S
Sebastian Brünink
Researcher at Humboldt University of Berlin
Publications - 19
Citations - 13721
Sebastian Brünink is an academic researcher from Humboldt University of Berlin. The author has contributed to research in topics: Virus & Coronavirus. The author has an hindex of 12, co-authored 18 publications receiving 9610 citations. Previous affiliations of Sebastian Brünink include Charité & University of Bonn.
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Journal ArticleDOI
Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-PCR.
Victor M. Corman,Olfert Landt,Marco Kaiser,Richard Molenkamp,Adam Meijer,Daniel K.W. Chu,Tobias Bleicker,Sebastian Brünink,Julia Schneider,Marie Luisa Schmidt,Daphne G.J.C. Mulders,Bart L. Haagmans,Bas van der Veer,Sharon van den Brink,Lisa Wijsman,Gabriel Goderski,Jean Louis Romette,Joanna Ellis,Maria Zambon,Malik Peiris,Herman Goossens,Chantal B.E.M. Reusken,Marion Koopmans,Christian Drosten +23 more
TL;DR: A validated diagnostic workflow for 2019-nCoV is presented, its design relying on close genetic relatedness of 2019- nCoV with SARS coronavirus, making use of synthetic nucleic acid technology.
Journal ArticleDOI
Virological assessment of hospitalized patients with COVID-2019.
Roman Wölfel,Victor M. Corman,Wolfgang Guggemos,M Seilmaier,Sabine Zange,Marcel A. Müller,Daniela Niemeyer,Terry Jones,Terry Jones,Patrick Vollmar,Camilla Rothe,Michael Hoelscher,Tobias Bleicker,Sebastian Brünink,Julia Schneider,Rosina Ehmann,Katrin Zwirglmaier,Christian Drosten,Clemens M. Wendtner +18 more
TL;DR: Detailed virological analysis of nine cases of coronavirus disease 2019 (COVID-19) provides proof of active replication of the SARS-CoV-2 virus in tissues of the upper respiratory tract.
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Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19.
Jenny Meinhardt,Josefine Radke,Carsten Dittmayer,Jonas Franz,Jonas Franz,Carolina Thomas,Carolina Thomas,Ronja Mothes,Michael Laue,Julia Schneider,Sebastian Brünink,Selina Greuel,Malte Lehmann,Olga Hassan,Tom Aschman,Elisa Schumann,Robert Lorenz Chua,Christian Conrad,Roland Eils,Roland Eils,Werner Stenzel,Marc Windgassen,Larissa Rößler,Hans-Hilmar Goebel,Hans R. Gelderblom,Hubert Martin,Andreas Nitsche,Walter J. Schulz-Schaeffer,Samy Hakroush,Martin Sebastian Winkler,Björn Tampe,Franziska Scheibe,Peter Körtvelyessy,Peter Körtvelyessy,Dirk Reinhold,Britta Siegmund,Anja A. Kühl,Sefer Elezkurtaj,David Horst,Lars Oesterhelweg,Michael Tsokos,Barbara Ingold-Heppner,Christine Stadelmann,Christian Drosten,Victor M. Corman,Helena Radbruch,Frank L. Heppner +46 more
TL;DR: The morphological changes associated with infection such as thromboembolic ischemic infarction of the CNS and evidence of SARS-CoV-2 neurotropism are described and presented.
Journal ArticleDOI
Assay optimization for molecular detection of Zika virus.
Victor M. Corman,Andrea Rasche,Cécile Baronti,Souhaib Aldabbagh,Daniel Cadar,Chantal Reusken,Suzan D. Pas,Abraham Goorhuis,Janke Schinkel,Richard Molenkamp,Beate M. Kümmerer,Tobias Bleicker,Sebastian Brünink,Monika Eschbach-Bludau,Anna Maria Eis-Hübinger,Marion Koopmans,Jonas Schmidt-Chanasit,Martin P. Grobusch,Xavier de Lamballerie,Christian Drosten,Jan Felix Drexler +20 more
TL;DR: Some published real-time RT–PCR assays might be unsuitable for Zika virus detection, due to the limited sensitivity and potential incompatibility with some strains.
Journal ArticleDOI
Characterization of a Novel Betacoronavirus Related to Middle East Respiratory Syndrome Coronavirus in European Hedgehogs
Victor M. Corman,René Kallies,Heike Philipps,Gertraude Göpner,Marcel A. Müller,Isabella Eckerle,Sebastian Brünink,Christian Drosten,Jan Felix Drexler +8 more
TL;DR: A novel betacoronavirus species in a phylogenetic sister relationship to MERS-CoV and clade c bat CoVs was detected and characterized on the whole-genome level, compatible with viral replication in the lower intestine and fecal-oral transmission.