S
Soledad Fernandez
Researcher at Ohio State University
Publications - 16
Citations - 2540
Soledad Fernandez is an academic researcher from Ohio State University. The author has contributed to research in topics: Stromal cell & Angiogenesis. The author has an hindex of 15, co-authored 16 publications receiving 2330 citations. Previous affiliations of Soledad Fernandez include University of Barcelona.
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Journal ArticleDOI
Pten in stromal fibroblasts suppresses mammary epithelial tumours
Anthony J. Trimboli,Carmen Z. Cantemir-Stone,Fu Li,Julie A. Wallace,Anand S. Merchant,Nicholas Creasap,John C. Thompson,Enrico Caserta,Hui Wang,Jean-Leon Chong,Shan Naidu,Guo Wei,Sudarshana M. Sharma,Julie A. Stephens,Soledad Fernandez,Metin N. Gurcan,Michael Weinstein,Sanford H. Barsky,Lisa D. Yee,Thomas J. Rosol,Paul C. Stromberg,Michael L. Robinson,Francois Pepin,Michael Hallett,Morag Park,Michael C. Ostrowski,Gustavo Leone,Gustavo Leone +27 more
TL;DR: The Pten–Ets2 axis is identified as a critical stroma-specific signalling pathway that suppresses mammary epithelial tumours and ameliorated disruption of the tumour microenvironment.
Journal ArticleDOI
Reprogramming of the tumour microenvironment by stromal PTEN-regulated miR-320
Agnieszka Bronisz,Jakub Godlewski,Julie A. Wallace,Anand Merchant,Michał Nowicki,Haritha Mathsyaraja,Ruchika Srinivasan,Anthony J. Trimboli,Anthony J. Trimboli,Chelsea K. Martin,Fu Li,Fu Li,Lianbo Yu,Soledad Fernandez,Thierry Pécot,Thierry Pécot,Thomas J. Rosol,Sean Cory,Michael Hallett,Morag Park,Melissa G. Piper,Clay B. Marsh,Lisa D. Yee,Rafael E. Jimenez,Gerard J. Nuovo,Sean E. Lawler,Ennio Antonio Chiocca,Gustavo Leone,Gustavo Leone,Michael C. Ostrowski +29 more
TL;DR: Estimation of the Pten–miR-320–Ets2-regulated secretome distinguished human normal breast stroma from tumour stroma and robustly correlated with recurrence in breast cancer patients is revealed.
Journal ArticleDOI
The effects of steep trendelenburg positioning on intraocular pressure during robotic radical prostatectomy.
Hamdy Awad,Scott Santilli,Matthew Ohr,Andrew G. Roth,Wendy Yan,Soledad Fernandez,Steven Roth,Vipul R. Patel +7 more
TL;DR: IOP reached peak levels at the end of steep Trendelenburg position (T5), on average 13 mm Hg higher than the preanesthesia induction (T1) value, whereas age, body mass index, blood loss, volume of IV fluid administered, mean airway pressure, and desflurane concentration were not predictive.
Journal ArticleDOI
RNA helicase A is necessary for translation of selected messenger RNAs
Tiffiney Roberts Hartman,Shuiming Qian,Cheryl Bolinger,Soledad Fernandez,Daniel R. Schoenberg,Kathleen Boris-Lawrie +5 more
TL;DR: This work shows that RHA recognizes a structured 5′-terminal post-transcriptional control element (PCE) of a retrovirus and the JUND growth-control gene and implicate RHA as an integrative effector in the continuum of gene expression from transcription to translation.
Journal ArticleDOI
NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors.
Christopher Alvarez-Breckenridge,Jianhua Yu,Richard L. Price,Jeffrey Wojton,Jason C. Pradarelli,Hsiaoyin Mao,Min Wei,Yan Wang,Shun He,Jayson Hardcastle,Soledad Fernandez,Balveen Kaur,Sean E. Lawler,Eric Vivier,Ofer Mandelboim,Alessandro Moretta,Michael A. Caligiuri,E. Antonio Chiocca,E. Antonio Chiocca +18 more
TL;DR: It is demonstrated that glioblastoma virotherapy is limited partially by an antiviral NK cell response involving specific NCRs, uncovering new potential targets to enhance cancer viroTherapy.