S
Stéphane Laurent
Researcher at University of Paris
Publications - 428
Citations - 82831
Stéphane Laurent is an academic researcher from University of Paris. The author has contributed to research in topics: Blood pressure & Arterial stiffness. The author has an hindex of 83, co-authored 424 publications receiving 75440 citations. Previous affiliations of Stéphane Laurent include University of Lausanne & Paris Descartes University.
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Journal ArticleDOI
Large artery stiffness in hypertension.
TL;DR: Clinical studies suggest that the presence of some genotypes may be a particularly important risk marker for arterial stiffness, and may modulate the effects of hypertension, ageing and lipids on large arteries, and these drugs may be particularly suitable for treating patients with increased arterial stiffening.
Journal ArticleDOI
Pharmacological modulation of arterial stiffness.
Pierre Boutouyrie,Patrick Lacolley,Marie Briet,Marie Briet,Véronique Regnault,Alice Stanton,Stéphane Laurent,Azra Mahmud +7 more
TL;DR: The quest continues for ‘de-stiffening drugs’, but so far only advanced glycation endproduct cross-link breakers have shown promise.
Journal ArticleDOI
Arterial stiffness and influences of the metabolic syndrome: A cross-countries study
Angelo Scuteri,Pedro Cunha,Enrico Agabiti Rosei,Jolita Badariere,Sofie Bekaert,John R. Cockcroft,Jorge Cotter,Francesco Cucca,Marc De Buyzere,Tim De Mayer,Luigi Ferrucci,Osca Franco,Nichola S. Gale,Thierry C. Gillebert,Michel Langlois,Aleksandras Laucevičius,Stéphane Laurent,Francesco Mattace Raso,Cristopher H. Morrell,Cristopher H. Morrell,Maria Lorenza Muiesan,Margaret Munnery,Rokas Navickas,Pedro Oliveira,Marco Orru,Maria Grazia Pilia,Ernst Rietzschel,Ligita Ryliskyte,Massimo Salvetti,David Schlessinger,Nuno Sousa,Christodoulos Stefanadis,James B. Strait,Caroline L. Van Daele,Isabel Villa,Charalambos Vlachopoulos,Jacqueline C. M. Witteman,Panagiotis Xaplanteris,Peter Nilsson,Edward G. Lakatta +39 more
TL;DR: Different component clusters of MetS showed varying associations with arterial stiffness (PWV) to an extent similar or greater than observed in subjects with alteration in all the five MetS components.
Journal ArticleDOI
Concept of Extremes in Vascular Aging
TL;DR: The concept of supernormal vascular aging (SUPERNOVA) was proposed in this article, which refers to the life of a supernova, a large explosion that takes place at the end of a star's life cycle.
Journal ArticleDOI
Increased Carotid Wall Stress in Vascular Ehlers-Danlos Syndrome
Pierre Boutouyrie,Dominique P. Germain,Jean-Noël Fiessinger,Brigitte Laloux,Jérôme Perdu,Stéphane Laurent +5 more
TL;DR: In vEDS patients, an abnormally low intima-media thickness generates a higher wall stress than in control subjects at the site of an elastic artery, which may increase the risk of arterial dissection and rupture.