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Stéphane Laurent

Researcher at University of Paris

Publications -  428
Citations -  82831

Stéphane Laurent is an academic researcher from University of Paris. The author has contributed to research in topics: Blood pressure & Arterial stiffness. The author has an hindex of 83, co-authored 424 publications receiving 75440 citations. Previous affiliations of Stéphane Laurent include University of Lausanne & Paris Descartes University.

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Association Between Local Pulse Pressure, Mean Blood Pressure, and Large-Artery Remodeling

TL;DR: Carotid pulse pressure was a strong independent determinant of carotid artery enlargement and wall thickening, whereas mean blood pressure and brachial pulse pressure were not, indicating the prominent influence of local pulsatile mechanical load on arterial remodeling.
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Structural and Genetic Bases of Arterial Stiffness

TL;DR: Data concerning the heritability of arterial stiffness are reviewed, and an integrated view of the structural and genetic determinants of arterials stiffness is proposed, based on a candidate gene approach and recent studies on gene expression profile.
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The Structural Factor of Hypertension Large and Small Artery Alterations

TL;DR: An integrated pathophysiological approach is proposed to better understand how the cross-talk between large and small artery changes interacts in pressure wave transmission, exaggerates cardiac, brain and kidney damage, and lead to cardiovascular and renal complications.
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Arterial stiffness and pulse pressure in CKD and ESRD

TL;DR: Premature vascular aging and arterial stiffening are observed with progression of chronic kidney disease and in end-stage renal disease and this accelerated aging is associated with outward remodeling of large vessels, characterized by increased arterial radius not totally compensated for by artery wall hypertrophy.