S
Stéphane Laurent
Researcher at University of Paris
Publications - 428
Citations - 82831
Stéphane Laurent is an academic researcher from University of Paris. The author has contributed to research in topics: Blood pressure & Arterial stiffness. The author has an hindex of 83, co-authored 424 publications receiving 75440 citations. Previous affiliations of Stéphane Laurent include University of Lausanne & Paris Descartes University.
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Journal ArticleDOI
Age-independent association between arterial and bone remodeling in mild-to-moderate chronic kidney disease
Marie Briet,Gérard Maruani,Cédric Collin,Erwan Bozec,Cédric Gauci,Pierre Boutouyrie,Pascal Houillier,Stéphane Laurent,Marc Froissart +8 more
TL;DR: Bone mineral density and serum marker of bone remodeling are independently correlated with arterial remodeling in CKD patients suggesting a crosstalk between kidney, arterial wall and bone.
Journal ArticleDOI
HPLC–DAD Analysis of Hydrochlorothiazide and Irbesartan in Hypertensive Patients on Fixed-Dose Combination Therapy
François Coudoré,Laurent Harvard,Sandrine Lefeuvre,Eliane M. Billaud,Philippe Beaune,Guillaume Bobrie,Michel Azizi,Patrice Prognon,Stéphane Laurent +8 more
TL;DR: A simple, sensitive, and selective high-performance liquid chromatographic (HPLC) method with diode-array detection was developed for simultaneous determination of HCTZ and IRBE levels in the plasma of hypertensive patients given a fixed combination of 12.5 mg H CTZ and 300 mg IRBE.
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Flow-dependent vasodilation of the brachial artery in essential hypertension: preliminary report.
Stéphane Laurent,Patrick Brunel,Patrick Lacolley,Eliane Billaud,Bruno Pannier,Michel E. Safar +5 more
TL;DR: The results suggest that velocity-dependent vasodilation of the brachial artery is not impaired in essential hypertension, and variation in the diameter of a large artery in humans is demonstrated.
Journal Article
[Local pulse pressure and regression of arterial wall hypertrophy during antihypertensive treatment. CELIMENE study. The Celiprolol Intima-Media Enalapril Efficacy study].
Pierre Boutouyrie,Bussy C,Tropeano Ai,Daniel Hayoz,Jan G. Hengstler,Dartois N,Brigitte Laloux,Brunner H,Stéphane Laurent +8 more
TL;DR: The regression of carotid artery wall hypertrophy during long-term antihypertensive treatment was dependent on the reduction in local PP rather than on the lowering of mean BP, and the effect of PP lowering on IMT reduction was observed at the site of an elastic artery but not at the sites of a muscular artery.
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Very-low-dose combination of perindopril and indapamide: efficacy on blood pressure and target-organ damage.
TL;DR: The proven efficacy on blood pressure and regression of target-organ damage with a good safety profile confirm that the new fixed-low-dose combination Per2/Ind0.625 is a valuable option in the first-line treatment of hypertension.