S
Sug Hyung Lee
Researcher at Catholic University of Korea
Publications - 463
Citations - 23933
Sug Hyung Lee is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Frameshift mutation & Germline mutation. The author has an hindex of 64, co-authored 454 publications receiving 21552 citations. Previous affiliations of Sug Hyung Lee include Chung-Ang University & The Catholic University of America.
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Journal Article
Alterations of Fas (APO-1/CD95) gene in transitional cell carcinomas of urinary bladder.
Sug Hyung Lee,Min Sun Shin,Won Sang Park,Su Young Kim,Seung Myung Dong,Jae Ho Pi,Hun Kyung Lee,Ho Sik Kim,Ja June Jang,Choo Soung Kim,Sang Ho Kim,Jung Young Lee,Nam Jin Yoo +12 more
TL;DR: The data suggest that alterations of the Fas gene might lead to the loss of its apoptotic function and contribute to the pathogenesis of some bladder cancers.
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Mutational analysis of FOXL2 codon 134 in granulosa cell tumour of ovary and other human cancers
TL;DR: The data indicate that the FOXL2 codon 134 mutation occurs exclusively in GCT and thecoma, and suggest the possibility that the development of most GCTs and a fraction of thecomas may be dependent on this mutation.
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Somatic mutations of CASP3 gene in human cancers.
Young Hwa Soung,Jong Woo Lee,Su Young Kim,Won Sang Park,Suk Woo Nam,Jung Young Lee,Nam Jin Yoo,Sug Hyung Lee +7 more
TL;DR: This is the first report on CASP3 gene mutations in human tumors; these data indicate that the caspase-3 gene is occasionally mutated inhuman tumors.
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Somatic mutations of the ERBB4 kinase domain in human cancers.
Young Hwa Soung,Jong Woo Lee,Su Young Kim,Young Pil Wang,Keon Hyun Jo,Seok Whan Moon,Won Sang Park,Suk Woo Nam,Jung Young Lee,Nam Jin Yoo,Sug Hyung Lee +10 more
TL;DR: This study demonstrated that in addition to EGFR and ERBB2, somatic mutation of the kinase domain of ER BB4 occurs in the common human cancers, and suggested that alterations of ERBB4‐mediated signaling pathway by ERBB 4 mutations may contribute to the development of human cancers.
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Nuclear localization of β-catenin is an important prognostic factor in hepatoblastoma
Won Sang Park,Ro Ra Oh,Jik Young Park,Pum Joon Kim,Min Sun Shin,Jong Heun Lee,Hong Sug Kim,Sug Hyung Lee,Su Young Kim,Yong Gyu Park,Won G. An,Han Seung Kim,Ja June Jang,Nam Jin Yoo,Jung Young Lee +14 more
TL;DR: In this study, mutational and immunohistochemical analyses of beta-catenin were performed in 30 hepatoblastomas, to assess the prevalence of alterations of the Wnt pathway with respect to clinicopathological parameters and survival.