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Sug Hyung Lee

Researcher at Catholic University of Korea

Publications -  463
Citations -  23933

Sug Hyung Lee is an academic researcher from Catholic University of Korea. The author has contributed to research in topics: Frameshift mutation & Germline mutation. The author has an hindex of 64, co-authored 454 publications receiving 21552 citations. Previous affiliations of Sug Hyung Lee include Chung-Ang University & The Catholic University of America.

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Mutational analysis of EGFR and K-RAS genes in lung adenocarcinomas

TL;DR: The data suggest that mutations of EGFR and K-RAS genes might separately, but not cooperatively, contribute to lung adenocarcinoma pathogenesis, and that EG FR and K -RAS mutants could separately be anti-neoplastic targets in lungAdenOCarcinomas.
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Inactivating mutations of the caspase-10 gene in gastric cancer.

TL;DR: The data presented here suggest that somatic alterations of the caspase-10 gene might contribute to the pathogenesis in a subset of gastric cancers through the loss of their apoptotic function.
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Frequent Somatic Mutations in Serine/Threonine Kinase 11/Peutz-Jeghers Syndrome Gene in Left-sided Colon Cancer

TL;DR: The results indicate that STK 11 is a tumor suppressor gene and that genetic changes of STK11 play an important role in left-sided colon cancer carcinogenesis.
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Genetic and expressional alterations of CHD genes in gastric and colorectal cancers

TL;DR: Genetic and expressional alterations of CHD genes in gastric and colorectal cancers and the role of EMTs in these cancers is investigated.
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Somatic mutations of Fas (Apo-1/CD95) gene in cutaneous squamous cell carcinoma arising from a burn scar.

TL;DR: The data show that some burn scar-related squamous cell carcinomas have Fas gene mutations in important regions for the apoptosis function and suggest that these mutations might be involved in the pathogenesis of burn scarThe results provide an important clue to understanding the difference between burn scar and conventional squamouscell carcinoma at the molecular level.