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Susan L. Naylor

Researcher at University of Texas Health Science Center at San Antonio

Publications -  83
Citations -  30322

Susan L. Naylor is an academic researcher from University of Texas Health Science Center at San Antonio. The author has contributed to research in topics: Gene & Chromosome 3. The author has an hindex of 37, co-authored 83 publications receiving 28891 citations.

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The DNA sequence, annotation and analysis of human chromosome 3

Donna M. Muzny, +154 more
- 27 Apr 2006 - 
TL;DR: Using genomic sequence from chimpanzee and rhesus macaque, the breakpoints defining a large pericentric inversion that occurred some time after the split of Homininae from Ponginae are characterized and an evolutionary history of the inversion is proposed.
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Assignment of the lactotransferrin gene to human chromosome 3 and to mouse chromosome 9

TL;DR: Southern blot analysis of DNA from mouse-Chinese hamster and human-mouse somatic cell hybrids maps the LTF gene to mouse chromosome 9 and to human chromosome 3, respectively, suggesting that LTF and associated genes of the transferrin family have existed together on the same chromosomal region for 300–500 million years.
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The DNF15S2 locus at 3p21 is transcribed in normal lung and small cell lung cancer.

TL;DR: Sequence analysis indicated that the DNF15S2 locus could potentially code for a previously unreported protein of 67 kDa which has 26 cysteine residues which has not been reported before.
Journal Article

An 80 Kb P1 clone from chromosome 3p21.3 suppresses tumor growth in vivo

TL;DR: Individual P1 clones were assayed for their ability to suppress the tumorigenicity of the mouse fibrosarcoma cell line A9 as assayed by injection of transfected A9 cells into athymic nude mice, and data functionally delimit a tumor suppressor locus to a region of 80 kb within a P1 clone at 3p21.3.