S
Sussan Nourshargh
Researcher at Queen Mary University of London
Publications - 148
Citations - 16130
Sussan Nourshargh is an academic researcher from Queen Mary University of London. The author has contributed to research in topics: Inflammation & Cell adhesion molecule. The author has an hindex of 59, co-authored 146 publications receiving 14197 citations. Previous affiliations of Sussan Nourshargh include National Institutes of Health & University of Cambridge.
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Journal ArticleDOI
Expression and function of junctional adhesion molecule-C in myelinated peripheral nerves.
Christoph Scheiermann,Paolo Meda,Michel Aurrand-Lions,Rime Madani,Yiangos Yiangou,Peter J. Coffey,Thomas E. Salt,Dominique Ducrest-Gay,Dorothée Caille,Owain W. Howell,Richard Reynolds,Alexander Lobrinus,Ralf H. Adams,Alan S.L. Yu,Praveen Anand,Beat A. Imhof,Sussan Nourshargh,Sussan Nourshargh +17 more
TL;DR: It is demonstrated that JAM-C is a component of the autotypic junctional attachments of Schwann cells and plays an important role in maintaining the integrity and function of myelinated peripheral nerves.
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Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factor
TL;DR: Results provide the first line of direct evidence for the involvement of endogenously formed PAF in the process of leukocyte extravasation induced by IL-1 in vivo.
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Junctional Adhesion Molecule-C Mediates Leukocyte Infiltration in Response to Ischemia Reperfusion Injury
Christoph Scheiermann,Bartomeu Colom,Paolo Meda,Nimesh S. A. Patel,Mathieu-Benoit Voisin,Alessandra Marrelli,Abigail Woodfin,Costantino Pitzalis,Christoph Thiemermann,Michel Aurrand-Lions,Beat A. Imhof,Sussan Nourshargh +11 more
TL;DR: A role for EC JAM-C is demonstrated in mediating leukocyte adhesion and transmigration in response to ischemia reperfusion (I/R) injury and the existence of a novel regulatory mechanism for redistribution and hence function of EC J AM-C in vivo is indicated.
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The peritoneal tumour microenvironment of high-grade serous ovarian cancer.
David A. Leinster,Hagen Kulbe,Gemma Everitt,Richard G. Thompson,Mauro Perretti,Felicity N. E. Gavins,Dianne Cooper,David Gould,Darren Ennis,Michelle Lockley,Iain A. McNeish,Sussan Nourshargh,Frances R. Balkwill +12 more
TL;DR: It is concluded that the multiple peritoneal tumour deposits found in HGSC patients can be modelled in the mouse and may be useful for assessing treatments that target the disseminated stage of this disease.
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Blockade of α6 integrin inhibits IL-1β- but not TNF-α-induced neutrophil transmigration in vivo
TL;DR: It is demonstrated that α6β1 blockade inhibits neutrophil migration induced by exogenous and endogenous IL‐1β but not TNF‐α, observations that are associated with increased expression of the integrin on transmigrated leukocytes.