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Susumu Kobayashi

Researcher at Beth Israel Deaconess Medical Center

Publications -  648
Citations -  23408

Susumu Kobayashi is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Total synthesis & Epidermal growth factor receptor. The author has an hindex of 62, co-authored 629 publications receiving 21514 citations. Previous affiliations of Susumu Kobayashi include Chiba University & University of Tokyo.

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K97-0239A and B, new inhibitors of macrophage foam cell formation, produced by Streptomyces sp. K97-0239

TL;DR: Two compounds, K97-0239A and B, were isolated from the culture broth of the producing strain, and their structures were elucidated by spectroscopic analyses including various NMR experiments, which caused a dose-dependent reduction in the number and size of cytosolic lipid droplets in macrophages.
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Retransplantation for de novo hepatocellular carcinoma in a liver allograft with recurrent hepatitis B cirrhosis 14 years after primary liver transplantation.

TL;DR: A 43-year-old Japanese man with end-stage hepatitis B-related cirrhosis had undergone orthotopic liver transplantation at Baylor University Medical Center, Dallas, Texas, in 1990 and developed severe chronic hepatitis despite interferon therapy between the first and the second posttransplant year in Japan.
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A novel lipid mediator, cyclic phosphatidic acid (cPA), and its biological functions.

TL;DR: This paper presents achanomizu University’s research in the field of biophysics and biochemistry of Tumor Biochemistry and its applications in the context of cancer and Cardiovascular Diseases.
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Synthesis of cis-Substituted β-Lactams, Potential Intermediates for cis-Carbapenems, from L-Aspartic Acid

TL;DR: In this paper, a 3S)-3-Benzyloxycarbonylamino-γ-butyrolactone was prepared by the regioselective reduction of L-aspartic acid.