S
Susumu Kobayashi
Researcher at Beth Israel Deaconess Medical Center
Publications - 648
Citations - 23408
Susumu Kobayashi is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Total synthesis & Epidermal growth factor receptor. The author has an hindex of 62, co-authored 629 publications receiving 21514 citations. Previous affiliations of Susumu Kobayashi include Chiba University & University of Tokyo.
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Heat shock protein inducer
TL;DR: In this paper, TIG-3 cell, a human fibroblast strain, is cultured at 37 degC, is provided with heat stress by adding a medium at 42 degC and cultibated at 42degC for a fixed time, then the compound as an active ingredient is pharmaceutically manufactured to give a heat shock protein inducer useful for treating cerebral nerve disease, cardiovascular disease, gastrointestinal disease, malignant tumor, infectious disease, infectious diseases, multiple sclerosis, etc.
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Natural Product Synthesis Using Halolactonization and Related Reactions
TL;DR: In this article, a review provides illustrative examples of the synthesis of natural products where halolactonization reaction plays an important role, and some related reactions are also described.
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Feasibility study of adjuvant chemotherapy with S-1 (TS-1; tegafur, gimeracil and oteracil potassium) for colorectal cancer.
Hidejiro Kawahara,Kazuhiro Watanabe,Takuro Ushigome,Rohta Noaki,Susumu Kobayashi,Katsuhiko Yanaga +5 more
TL;DR: Three-week method of S-1 administration had good feasibility, easily manageable toxicity, high accumulated dose in one year and good compliance, and may be a standard adjuvant chemotherapy schedule for colorectal cancer.
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Stereoselective Synthesis of Functionalized Spiro[4.5]decanes by Claisen Rearrangement of Bicyclic Dihydropyrans
TL;DR: In this paper, a functionalized spiro[4.5]decane framework was synthesized by the Claisen rearrangement of 4-substituted bicyclic dihydropyrans in a highly stereoselective fashion.