S
Susumu Kobayashi
Researcher at Beth Israel Deaconess Medical Center
Publications - 648
Citations - 23408
Susumu Kobayashi is an academic researcher from Beth Israel Deaconess Medical Center. The author has contributed to research in topics: Total synthesis & Epidermal growth factor receptor. The author has an hindex of 62, co-authored 629 publications receiving 21514 citations. Previous affiliations of Susumu Kobayashi include Chiba University & University of Tokyo.
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Targeting transcription factors in acute myeloid leukemia.
TL;DR: This review focuses on transcription factors that play important roles in leukemogenesis and current efforts and prospects in the development of transcriptional therapy, and believes that such a therapeutic approach will benefit patients with cancers that involve acute myeloid leukemia in the near future.
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Stereocontrolled preparation of 1,2-diol with quaternary chiral center
TL;DR: In this article, an enantio-and stereoselective construction of 1,2-diols including a quaternary chiral center was achieved by a titanium-mediated aldol reaction of lactates bearing chiral oxazolidine-2-ones.
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Identification of C10 biotinylated camptothecin (CPT-10-B) binding peptides using T7 phage display screen on a QCM device.
Yoichi Takakusagi,Kaori Takakusagi,Kouji Kuramochi,Susumu Kobayashi,Fumio Sugawara,Kengo Sakaguchi +5 more
TL;DR: The peptide sequence displayed on phages A-C is consistent with chemical and biological studies of the interaction of CPTs with topoisomerase I, human E prostanoid receptor third cytoplasmic polypeptide, and a series of esterases.
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Prophylactic excision of the gallbladder and bile duct for patients with pancreaticobiliary maljunction.
Susumu Kobayashi,Takehide Asano,Masato Yamasaki,Takashi Kenmochi,Kenichi Saigo,Takenori Ochiai +5 more
TL;DR: The gallbladder carries a high risk for carcinogenesis in all types of dilation in patients with PBM and cystic dilation, and Prophylactic cholecystectomy should be recommended for all dilation types.
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A new glycosylation reaction based on a “remote activation concept”: glycosyl 2-pyridinecarboxylate as a novel glycosyl donor
TL;DR: In this article, a novel glycosyl donor based on a variation of the Remote Activation Concept was designed, which could be effected with copper (II) triflate in Et2O or tin (II), in CH3CN, respectively.