T
Thomas Martin
Researcher at University of California, San Francisco
Publications - 311
Citations - 17918
Thomas Martin is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Medicine & Exocytosis. The author has an hindex of 73, co-authored 242 publications receiving 15771 citations. Previous affiliations of Thomas Martin include Institut national de la recherche agronomique & University of Western Australia.
Papers
More filters
Journal ArticleDOI
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
David S. Siegel,Thomas Martin,Michael Wang,Ravi Vij,Andrzej Jakubowiak,Sagar Lonial,Suzanne Trudel,Vishal Kukreti,Nizar J. Bahlis,Melissa Alsina,Asher Chanan-Khan,Francis K. Buadi,Frederic J. Reu,George Somlo,Jeffrey A. Zonder,Kevin W. Song,A. Keith Stewart,Edward A. Stadtmauer,Lori Kunkel,Sandra Wear,Alvin F. Wong,Robert Z. Orlowski,Sundar Jagannath +22 more
TL;DR: Durable responses and an acceptable tolerability profile in this heavily pretreated population demonstrate the potential of carfilzomib to offer meaningful clinical benefit.
Journal ArticleDOI
ATP-dependent inositide phosphorylation required for Ca 2+ -activated secretion
Jesse C. Hay,Phillip L Fisette,Glenn H. Jenkins,Kiyoko Fukami,Tadaomi Takenawa,Richard A. Anderson,Thomas Martin +6 more
TL;DR: The results indicate that lipid kinase-mediated phosphorylation is an important basis for ATP use in the exocytotic pathway.
Journal ArticleDOI
Ciltacabtagene autoleucel, a B-cell maturation antigen-directed chimeric antigen receptor T-cell therapy in patients with relapsed or refractory multiple myeloma (CARTITUDE-1): a phase 1b/2 open-label study
Jesus G. Berdeja,Deepu Madduri,Saad Z. Usmani,Andrzej Jakubowiak,Mounzer Agha,Adam D. Cohen,A. Keith Stewart,Parameswaran Hari,Myo Htut,Alexander M. Lesokhin,Abhinav Deol,Nikhil C. Munshi,Elizabeth O'Donnell,David Avigan,Indrajeet Singh,Enrique Zudaire,Tzu-Min Yeh,Alicia J. Allred,Yunsi Olyslager,Arnob Banerjee,Carolyn C. Jackson,Jenna D. Goldberg,Jordan M. Schecter,William Deraedt,Sen Hong Zhuang,Jeffrey R. Infante,Dong Geng,Xiaoling Wu,Marlene J Carrasco-Alfonso,Muhammad Akram,Farah Hossain,Syed Rizvi,Frank Fan,Yi Lin,Thomas Martin,Sundar Jagannath +35 more
TL;DR: The CARITUDE-1 trial as discussed by the authors evaluated the safety and clinical activity of ciltacabtagene autoleucel (cilta-cel), a chimeric antigen receptor T-cell therapy with two B-cell maturation antigen-targeting single-domain antibodies.
Journal ArticleDOI
PHOSPHOINOSITIDE LIPIDS AS SIGNALING MOLECULES: Common Themes for Signal Transduction, Cytoskeletal Regulation, and Membrane Trafficking
TL;DR: Common themes of localized signal generation and the spatially localized recruitment of effector proteins appear to underlie mechanisms employed in signal transduction, cytoskeletal, and membrane trafficking events.
Journal ArticleDOI
The b alleles of U. maydis, whose combinations program pathogenic development, code for polypeptides containing a homeodomain-related motif
Burkhard Schulz,Flora Banuett,Marlis Dahl,Ramona Schlesinger,Willi Schäfer,Thomas Martin,Ira Herskowitz,Regine Kahmann +7 more
TL;DR: It is proposed that combinatorial interactions between b polypeptides generate regulatory proteins that determine the developmental program of the fungus.