T
Tobias R. Kollmann
Researcher at Telethon Institute for Child Health Research
Publications - 198
Citations - 10070
Tobias R. Kollmann is an academic researcher from Telethon Institute for Child Health Research. The author has contributed to research in topics: Vaccination & Immune system. The author has an hindex of 48, co-authored 181 publications receiving 7929 citations. Previous affiliations of Tobias R. Kollmann include Yeshiva University & University of Washington.
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Journal ArticleDOI
Early infancy microbial and metabolic alterations affect risk of childhood asthma
Marie-Claire Arrieta,Leah T. Stiemsma,Pedro A. Dimitriu,Lisa Thorson,Shannon L. Russell,Sophie Yurist-Doutsch,Boris Kuzeljevic,Matthew J. Gold,Heidi Britton,Diana L. Lefebvre,Padmaja Subbarao,Piush J. Mandhane,Allan B. Becker,Kelly M. McNagny,Malcolm R. Sears,Tobias R. Kollmann,William W. Mohn,Stuart E. Turvey,B. Brett Finlay +18 more
TL;DR: It is reported in a longitudinal human study that infants at risk of asthma have transient gut microbial dysbiosis during the first 100 days of life, and certain bacterial genera were decreased in these children, suggesting a potential causative role of the loss of these microbes.
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Innate Immune Function by Toll-like Receptors: Distinct Responses in Newborns and the Elderly
TL;DR: Development patterns of distinct Toll-like-receptor-mediated immune responses come to light when one contrasts innate immune development at the beginning of life with that toward the end of life, and these developmental patterns of innate cytokine responses correlate with clinical patterns of susceptibility to disease.
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Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults
Tobias R. Kollmann,Juliet Crabtree,Annie Rein-Weston,Darren Blimkie,Francis Thommai,Xiu Yu Wang,Pascal M. Lavoie,Jeff Furlong,Edgardo S. Fortuno,Adeline M. Hajjar,Natalie Hawkins,Steven G. Self,Christopher B. Wilson +12 more
TL;DR: The data suggest a robust if not enhanced capacity of the neonate vs the adult white-blood cell TLR-mediated response to support Th17- and Th2-type immunity, which promotes defense against extracellular pathogens, but a reduced capacity toSupport Th1-type responses, which promote defense against intracellular pathogens.
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MIFlowCyt: the minimum information about a Flow Cytometry Experiment.
Jamie A. Lee,Josef Spidlen,Keith S. Boyce,Jennifer Cai,Nicholas D. Crosbie,Mark E. Dalphin,Jeff Furlong,Maura Gasparetto,M. W. Goldberg,Elizabeth M. Goralczyk,Bill Hyun,Kirstin Jansen,Tobias R. Kollmann,Megan Kong,Robert C. Leif,Shannon K. McWeeney,Thomas D. Moloshok,Wayne A. Moore,Garry P. Nolan,John P. Nolan,Janko Nikolich-Zugich,David Parrish,Barclay Purcell,Yu Qian,Biruntha Selvaraj,Clayton A. Smith,Olga Tchuvatkina,Anne M. Wertheimer,Peter Wilkinson,Christopher B. Wilson,James C. S. Wood,Robert Zigon,Richard H. Scheuermann,Ryan R. Brinkman +33 more
TL;DR: The MIFlowCyt standard includes recommendations about descriptions of the specimens and reagents included in the FCM experiment, the configuration of the instrument used to perform the assays, and the data processing approaches used to interpret the primary output data.
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Immunological mechanisms of vaccine-induced protection against COVID-19 in humans.
TL;DR: Most COVID-19 vaccines have been designed to elicit immune responses, ideally neutralizing antibodies (NAbs), against the SARS-CoV-2 spike protein this article.