U
Ulrike Holzgrabe
Researcher at University of Würzburg
Publications - 591
Citations - 11158
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Allosteric regulation & Capillary electrophoresis. The author has an hindex of 45, co-authored 566 publications receiving 9806 citations. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Journal Article
An LC–MS/MS procedure for the quantification of naproxen in human plasma: Development, validation, comparison with other methods, and application to a pharmacokinetic study
TL;DR: A sensitive, precise and accurate quantitative LC-MS/MS method for the measurement of naproxen in human plasma was developed and completely validated according to current FDA and EMA guidelines.
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Capillary electrophoresis separation of phenethylamine enantiomers using amino acid based ionic liquids.
Joachim Wahl,Ulrike Holzgrabe +1 more
TL;DR: Imino acid based ionic liquids with different proteinogenic l‐amino acids were prepared and tested as background electrolyte additives for the separation of phenethylamine enantiomers and best separations were achieved using tetrabutylammonium l‐argininate in a phosphate buffer containing &bgr;‐cyclodextrin.
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Determination of free fatty acids in pharmaceutical lipids by 1H NMR and comparison with the classical acid value
TL;DR: A new (1)H NMR approach to determine the acid value is described and the method was validated using a statistical approach based on a variance components model.
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Microwave-enhanced hydrogenations at medium pressure using a newly constructed reactor
TL;DR: In this article, the microwave-assisted hydrogenation of strychnine and dearomatization were compared with classical hydrogenations. And the superiority of microwave assisted hydrogenation was demonstrated.
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A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion.
Sabine Niedermeier,Katrin Singethan,Sebastian Georgios Rohrer,Magnus Matz,Markus Kossner,Sandra Diederich,Andrea Maisner,Jens Schmitz,Georg Hiltensperger,Knut Baumann,Ulrike Holzgrabe,Jürgen Schneider-Schaulies +11 more
TL;DR: Five compounds successfully inhibiting NiV envelope protein-induced cell fusion are found, and molecular modeling indicated that compound 19 fits well into a particular protein cavity present on the NiV F protein that is important for the fusion process.