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Ulrike Holzgrabe
Researcher at University of Würzburg
Publications - 591
Citations - 11158
Ulrike Holzgrabe is an academic researcher from University of Würzburg. The author has contributed to research in topics: Allosteric regulation & Capillary electrophoresis. The author has an hindex of 45, co-authored 566 publications receiving 9806 citations. Previous affiliations of Ulrike Holzgrabe include Jagiellonian University & University of Illinois at Chicago.
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Indirect Enantioseparation of Amino Acids by CE Using Automated In-Capillary Derivatization with ortho-Phthalaldehyde and N-Acetyl-l-Cysteine
TL;DR: In this paper, a simple CE method for the assessment of enantiomeric purity of individual amino acids (AAs) was presented, where the AAs were derivatized with ortho-phthalaldehyde and a thiol in the capillary by means of successive hydrodynamic injections (5 s, 0.5 s).
Journal Article
Antitrypanosomal naphthylisoquinoline alkaloids and related compounds.
TL;DR: The results demonstrate that naphthylisoquinoline alkaloids constitute an interesting novel class of antitrypanosomal compounds worth further optimization.
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Allosteric site in M2 acetylcholine receptors: evidence for a major conformational change upon binding of an orthosteric agonist instead of an antagonist
TL;DR: It is concluded that the common allosteric site is still present in OxoM-liganded M2 receptors, but its spatial conformation is considerably altered compared with NMS-liganding receptors.
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Future Information Technology Tools for Fighting Substandard and Falsified Medicines in Low- and Middle-Income Countries.
TL;DR: Information technology tools including medicines authentication tools as mobile apps and messaging service, 2D barcoding approaches with drug safety alert systems, web based drug safety alerts, radiofrequency identification tags, databases to support visual inspection, digital aids to enhance the performance of quality evaluation kits, reference libraries for identification of falsified and substandard medicines are reviewed.
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Laser-induced fluorescence-capillary electrophoresis and fluorescence microplate reader measurement: two methods to quantify the effect of antibiotics.
TL;DR: The new LIF-CE method, which based on the use of a second unlabeled bacteria injection as a stacking front, allowed drawing conclusions from the electrophoretic profile about the constitution of the bacterial population can be directly observed in the presence of different antibiotics.